Anti-Mi2 dermatomyositis revisited: pure DM phenotype with muscle fiber necrosis and high risk of malignancy - École Nationale Supérieure de Biologie Appliquée à la Nutrition et à l'Alimentation ENSBANA Accéder directement au contenu
Communication Dans Un Congrès Année : 2017

Anti-Mi2 dermatomyositis revisited: pure DM phenotype with muscle fiber necrosis and high risk of malignancy

G. Monseau
  • Fonction : Auteur
B. Bienvenu
  • Fonction : Auteur

Résumé

Anti-Mi2 are dermatomyositis-specific autoantibodies (Aabs) that have been associated, in small cohorts, with a good prognosis possibly related to a lower malignancy risk. Our objective was to describe the phenotype of anti-Mi-2 dermatomyositis (DM) in a larger cohort. A national multicenter retrospective cohort study was performed including all patients with a clinical phenotype suggestive of DM (cutaneous manifestations and/or muscle involvement) and a positive anti-Mi2 Aabs. Medical records were retrospectively reviewed to assess clinical and histological features, and presence of cancer occurring ± 3 years of diagnosing myositis (CAM).

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Dates et versions

hal-01664160 , version 1 (14-12-2017)

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Citer

O. Landon-Cardinal, G. Monseau, Y. Schoindre, A. Rigolet, N. Champtiaux, et al.. Anti-Mi2 dermatomyositis revisited: pure DM phenotype with muscle fiber necrosis and high risk of malignancy. 22nd International Congress of the World Muscle Society, Oct 2017, Saint Malo, France. pp.S153, ⟨10.1016/j.nmd.2017.06.218⟩. ⟨hal-01664160⟩
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