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Poster De Conférence Année : 2015

Antioxidative and wound healing properties of Crateva adansonii DC

Résumé

Leaves of Crateva adansonii DC, a small bush found in Togo, are widely used in traditional medicine to cure infectious abscess. Traditional healers harvest only young leaves and sprouts early in the morning in order to prepare their drugs. To validate this ancestral practice, we performed a phytochemical screening of various C. adansonii leaves samples collected in different places, at different time and at different ages. Using antioxidant activity as selection criteria, optimal extracts were obtained with sprout leaves, collected at 5:00 am in Djidjolé. Wound healing potential was then investigated for several extracts in vitro on keratinocytes stimulated by Staphylococcus aureus proteins. Anti-inflammatory activity was highlighted with flavonoids-rich extracts, especially against TNFa. Those results validate the traditional practices and the potential of C. adansonii as wound healing drug.
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Dates et versions

hal-01240235 , version 1 (03-06-2020)

Identifiants

  • HAL Id : hal-01240235 , version 1
  • PRODINRA : 338442

Citer

Kplolali Ahama-Esseh, Leslie Boudesocque-Delaye, Charles Bodet, A Quashie-Mensah-Attoh, C. Desouza, et al.. Antioxidative and wound healing properties of Crateva adansonii DC. 7. International Conference on Polyphenols and Health, Oct 2015, Tours, France. , 322 p., 2015, ICPH 2015. ⟨hal-01240235⟩
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