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Key numbers
Last submissions
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Caroline Le Dour, Maria Chatzifrangkeskou, Coline Macquart, Maria M Magiera, Cécile Peccate, et al.. Actin-microtubule cytoskeletal interplay mediated by MRTF-A/SRF signaling promotes dilated cardiomyopathy caused by LMNA mutations. Nature Communications, 2022, 13 (1), pp.7886. ⟨10.1038/s41467-022-35639-x⟩. ⟨hal-03921784⟩
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Clémence Labasse, Guy Brochier, Ana-Lia Taratuto, Bruno Cadot, John Rendu, et al.. Severe ACTA1-related nemaline myopathy: intranuclear rods, cytoplasmic bodies, and enlarged perinuclear space as characteristic pathological features on muscle biopsies. Acta Neuropathologica Communications, 2022, 10 (1), pp.101. ⟨10.1186/s40478-022-01400-0⟩. ⟨hal-03820052⟩
Open Access
55 %
Keywords
Mechanotransduction
DMyHC
Alpha-actinin-2
Antisense oligonucleotides
AAV8
Biomarkers
Adeno-associated virus
Myopathie
CTL
Cell signaling
BAF
Cross-presentation
Outflow tract
RNA interference
A-type lamins
Duchenne muscular dystrophy DMD
Adhesion
AFM
Dynamin
Developmental biology
Cytoskeleton
Cardiomyopathies
Duchenne Muscular Dystrophy
Centronuclear myopathy
Autophagy cellular
Adult patients
Autophagy
Nucleus
Autophagosome
Atrial heart defects
Cross-bridge kinetics
Muscle
Lamin
Diaphragm
Allele-specific silencing
BAR proteins
Cellules de crête neurale
Dystrophie musculaire de Duchenne
Cell migration
Skin
Correlative microscopy
CAV-3 gene
Allele‐specific silencing therapy
Actin
Clathrine
Dullard
Adeno-associated virus vector
Dynamin overexpression
Coeur
Satellite cell
Neural crest cells
Amphiphysin
Congenital myopathy
Muscular dystrophy
Charcot-Marie-Tooth
Dystrophie musculaire d'Emery Dreifuss
Skeletal muscle
Biophysics
Cytosquelette
Caveolins
Ctdnep1
Becker muscular dystrophy BMD
Developmental myosin heavy chain
Nesprin
Core myopathy
BMP signaling
AD-CNM
Endocytosis
Dominant centronuclear myopathy
Cavins
Autophagosome maturation
Domaine LEM
Caveolin
Disease modifiers
Cavéoles
Myosin
Allele specific RNA interference
Cellular neuroscience
Cancer
Nuclear envelope
Caveolae
Adeno-Associated virus
Actin nucleus
Gene therapy
Atrial cardiac defects
DNM2
Dynamin 2
AAV
Clathrin
ACTN2
Dynamine
Migration
Myopathy
Cell proliferation
Duchenne muscular dystrophy
Animal models of human disease
Autosomal dominant centronuclear myopathy
Cardiotoxin
Allele-specific silencing therapy
Disease heterogeneity