188Re-SSS lipiodol: radiolabelling and biodistribution following injection into the hepatic artery of rats bearing hepatoma, Nuclear Medicine Communications, vol.25, issue.10, pp.1007-1020, 2004. ,
DOI : 10.1097/00006231-200410000-00004
Liver embolizations in oncology: A review, Medical Oncology, vol.182, issue.Suppl 1, pp.1-11, 2008. ,
DOI : 10.1007/s12032-007-0039-3
Fibrin glue system for adjuvant brachytherapy of brain tumors with 188Re and 186Re-labeled microspheres, European Journal of Pharmaceutics and Biopharmaceutics, vol.65, issue.3, pp.282-290, 2007. ,
DOI : 10.1016/j.ejpb.2006.10.016
A comparison of lipiodol chemoembolization and conservative treatment for unresectable hepatocellular carcinoma. Groupe d'Etude et de Traitement du Carcinome Hepatocellulaire, N Engl J Med, vol.332, pp.1256-61, 1995. ,
Radioembolization with yttrium-90 glass microspheres in hepatocellular carcinoma: European experience on safety and long-term survival, Hepatology, vol.74, issue.5, pp.1741-1750, 2010. ,
DOI : 10.1002/hep.23944
Vascular invasion and histopathologic grading determine outcome after liver transplantation for hepatocellular carcinoma in cirrhosis, Hepatology, vol.33, issue.5, pp.1080-1086, 2001. ,
DOI : 10.1053/jhep.2001.23561
Role of Kupffer Cells in Iodized Oil Embolization, Investigative Radiology, vol.29, issue.11, pp.990-993, 1994. ,
DOI : 10.1097/00004424-199411000-00007
Liver resection and transplantation in the management of hepatocellular carcinoma: a review, Exp Clin Transplant, vol.4, issue.2, pp.549-58, 2006. ,
Y Therapy of Liver Cancer, Technology in Cancer Research & Treatment, vol.48, issue.3, pp.253-62, 2010. ,
DOI : 10.1177/153303461000900304
Liver Transplantation for the Treatment of Small Hepatocellular Carcinomas in Patients with Cirrhosis, New England Journal of Medicine, vol.334, issue.11, pp.693-702, 1996. ,
DOI : 10.1056/NEJM199603143341104
Percutaneous Ablation of Hepatocellular Carcinoma: Current Status, Journal of Vascular and Interventional Radiology, vol.21, issue.8, pp.204-217, 2010. ,
DOI : 10.1016/j.jvir.2009.11.025
Chelated Hydrazido(3???)rhenium(V) Complexes:?? On the Way to the Nitrido???M(V) Core (M = Tc, Re), Inorganic Chemistry, vol.41, issue.6, pp.1591-1598, 2002. ,
DOI : 10.1021/ic0110979
Intra-arterial therapy with cisplatin suspension in lipiodol and 5-fluorouracil for hepatocellular carcinoma with portal vein tumour thrombosis, Alimentary Pharmacology & Therapeutics, vol.249, issue.4, pp.543-50, 2010. ,
DOI : 10.1111/j.1365-2036.2010.04379.x
The changing pattern of epidemiology in hepatocellular carcinoma, Digestive and Liver Disease, vol.42, issue.3, pp.206-220, 2010. ,
DOI : 10.1016/S1590-8658(10)60507-5
Hepatocellular carcinoma detected by iodized oil. Use of anticancer agents., Radiology, vol.154, issue.1, pp.25-34, 1985. ,
DOI : 10.1148/radiology.154.1.2981114
Hepatic artery injection of I-131-labeled lipiodol. Part I. Biodistribution study results in patients with hepatocellular carcinoma and liver metastases., Radiology, vol.168, issue.2, pp.541-546, 1988. ,
DOI : 10.1148/radiology.168.2.2839866
Randomized controlled trial for hepatocellular carcinoma with portal vein thrombosis: intra-arterial iodine-131-iodized oil versus medical support, J Nucl Med, vol.35, issue.11, pp.1782-1789, 1994. ,
Prospective randomized trial of chemoembolization versus intra-arterial injection of 131I-labeled-iodized oil in the treatment of hepatocellular carcinoma., Hepatology, vol.26, issue.5, pp.1156-61, 1997. ,
DOI : 10.1053/jhep.1997.v26.pm0009362356
Liver Transplantation for Hepatocellular Carcinoma: Results of Down-Staging in Patients Initially Outside the Milan Selection Criteria, American Journal of Transplantation, vol.12, issue.12, pp.2547-57, 2008. ,
DOI : 10.1111/j.1600-6143.2008.02409.x
131I lipiodol therapy for unresectable hepatocellular carcinoma, ANZ Journal of Surgery, vol.72, issue.3, pp.210-214, 2002. ,
DOI : 10.1007/s005340050179
Prospective comparison of transcatheter arterial chemoembolization with Lipiodol-epirubicin and Lipiodol-cisplatin for treatment of recurrent hepatocellular carcinoma, Japanese Journal of Radiology, vol.74, issue.S6, pp.362-370, 2010. ,
DOI : 10.1007/s11604-010-0436-y
Treatment of Unresectable Hepatocellular Carcinoma with Use of 90Y Microspheres (TheraSphere): Safety, Tumor Response, and Survival, Journal of Vascular and Interventional Radiology, vol.16, issue.12, pp.1627-1666, 2005. ,
DOI : 10.1097/01.RVI.0000184594.01661.81
The Current Practice of Transarterial Chemoembolization for the Treatment of Hepatocellular Carcinoma, Korean Journal of Radiology, vol.10, issue.5, pp.425-459, 2009. ,
DOI : 10.3348/kjr.2009.10.5.425
Hepatic artery infusion and chemoembolization in the management of liver metastases, Cardiovascular and Interventional Radiology, vol.260, issue.7, pp.153-60, 1990. ,
DOI : 10.1007/BF02575467
Radiolabelling of lipiodol with generator-produced 188Re for hepatic tumor therapy, Applied Radiation and Isotopes, vol.47, issue.3, pp.267-71, 1996. ,
DOI : 10.1016/0969-8043(95)00300-2
Hepatic artery injection of Yttrium-90-lipiodol: biodistribution in rats with hepatoma, J Nucl Med, vol.37, issue.2, pp.332-337, 1996. ,
Future perspectives in hepatocellular carcinoma, Digestive and Liver Disease, vol.42, issue.3, pp.302-311, 2010. ,
DOI : 10.1016/S1590-8658(10)60521-X
Labeling and biodistribution of different particle materials for radioembolization therapy with 188Re, Applied Radiation and Isotopes, vol.62, issue.5, pp.745-50, 2005. ,
DOI : 10.1016/j.apradiso.2004.11.003
Sequential use of transarterial chemoembolization and percutaneous cryosurgery for hepatocellular carcinoma, World Journal of Gastroenterology, vol.15, issue.29, pp.3664-3673, 2009. ,
DOI : 10.3748/wjg.15.3664
Hepatocellular carcinoma: a global view, Nature Reviews Gastroenterology & Hepatology, vol.150, issue.8, pp.448-58, 2010. ,
DOI : 10.1038/nrgastro.2010.100
Liver transplantation for hepatocellular carcinoma: Expansion of the tumor size limits does not adversely impact survival, Hepatology, vol.33, issue.6, pp.1394-403, 2001. ,
DOI : 10.1053/jhep.2001.24563
Somatostatin receptor scintigraphy in central nervous system tumors: role of blood-brain barrier permeability, J Nucl Med, vol.36, pp.403-410, 1995. ,
Brain drug targeting: a computational approach for overcoming blood???brain barrier, Drug Discovery Today, vol.14, issue.21-22, pp.1030-1036, 2009. ,
DOI : 10.1016/j.drudis.2009.07.009
Combined effect of gefitinib ('Iressa', ZD1839) and targeted radiotherapy with 211 At-EGF, European Journal of Nuclear Medicine and Molecular Imaging, vol.30, issue.10, pp.1348-1356, 2003. ,
DOI : 10.1007/s00259-003-1308-9
Improved radiotracing of oxytocin receptor-expressing tumours using the new [111In]-DOTA-Lys8-deamino-vasotocin analogue, British Journal of Cancer, vol.89, issue.5, pp.930-936, 2003. ,
DOI : 10.1038/sj.bjc.6601189
Radiation dosimetry of 131I-chlorotoxin for targeted radiotherapy in glioma-bearing mice, Journal of Neuro-Oncology, vol.21, issue.2, pp.113-119, 2005. ,
DOI : 10.1007/s11060-004-0890-4
Somatostatin Receptors, Trends in Endocrinology and Metabolism, vol.8, issue.10 ,
DOI : 10.1016/S1043-2760(97)00168-9
Functional effects of somatostatin receptor 1 activation on synaptic transmission in the mouse hippocampus, Journal of Neurochemistry, vol.12, issue.6, pp.1466-1477, 2009. ,
DOI : 10.1111/j.1471-4159.2009.06423.x
Distribution and biochemical characterization of somatostatin receptors in tumors of the human central nervous system, Cancer Res, vol.47, pp.5758-5764, 1987. ,
via a Phosphotyrosine Phosphatase-??-Dependent Inhibition of Extracellularly Regulated Kinase-1/2, Endocrinology, vol.149, issue.9, pp.4736-4746, 2008. ,
DOI : 10.1210/en.2007-1762
Somatostatin and somatostatin receptors in the diagnosis and treatment of gliomas, Journal of Neuro-Oncology, vol.35, issue.3, pp.353-364, 1997. ,
DOI : 10.1023/A:1005893223090
Coincidence of EGF receptors and somatostatin receptors in meningiomas but inverse, differentiation-dependent relationship in glial tumors, Am J Pathol, vol.134, pp.337-344, 1989. ,
Somatostatin and Its Receptor Family, Frontiers in Neuroendocrinology, vol.20, issue.3, pp.157-198, 1999. ,
DOI : 10.1006/frne.1999.0183
Somatostatin analogs ??? from new molecules to new applications, Current Opinion in Pharmacology, vol.4, issue.6, pp.608-613, 2004. ,
DOI : 10.1016/j.coph.2004.06.010
Locoregional regulatory peptide receptor targeting with the diffusible somatostatin analogue 90Y-labeled DOTA0-D-Phe1-Tyr3-octreotide (DOTATOC): a pilot study in human gliomas, Clin Cancer Res, vol.5, pp.1025-1033, 1999. ,
DOTATOC: a powerful new tool for receptor-mediated radionuclide therapy, Eur J Nucl Med, vol.24, pp.792-795, 1997. ,
Yttrium-90-labelled somatostatin-analogue for cancer treatment, The Lancet, vol.351, issue.9100, pp.417-418, 1998. ,
DOI : 10.1016/S0140-6736(05)78355-0
-octreotide radiopeptide brachytherapy, Cancer, vol.19, issue.1-2, pp.869-873, 2005. ,
DOI : 10.1002/cncr.20822
URL : https://hal.archives-ouvertes.fr/hal-00316046
Receptor radionuclide therapy with 90Y-[DOTA]0-Tyr3-octreotide (90Y-DOTATOC) in neuroendocrine tumours, European Journal of Nuclear Medicine and Molecular Imaging, vol.31, issue.7, pp.1038-1046, 2004. ,
DOI : 10.1007/s00259-004-1571-4
Successful diffusible brachytherapy (dBT) of a progressive low-grade astrocytoma using the locally injected peptidic vector and somatostatin analogue [90Y]-DOTA0-D-Phe1-Tyr3-octreotide (DOTATOC), Swiss Med Wkly, vol.131, pp.640-644, 2001. ,
Local injection of the 90Y-labelled peptidic vector DOTATOC to control gliomas of WHO grades II and III: an extended pilot study, European Journal of Nuclear Medicine and Molecular Imaging, vol.29, issue.4, pp.486-493, 2002. ,
DOI : 10.1007/s00259-001-0717-x
Yttrium-90 and indium-111 labelling, receptor binding and biodistribution of [DOTA0,d-Phe1,Tyr3]octreotide, a promising somatostatin analogue for radionuclide therapy, European Journal of Nuclear Medicine, vol.265, issue.4, pp.368-371, 1997. ,
DOI : 10.1007/BF00881807
Response of Recurrent High-Grade Glioma to Treatment with 90Y-DOTATOC, Journal of Nuclear Medicine, vol.51, issue.3, pp.397-400, 2010. ,
DOI : 10.2967/jnumed.109.072819
Cancer nanotargeted radiopharmaceuticals for tumor imaging and therapy, Anticancer Res, vol.29, pp.4107-4118, 2009. ,
DOI : 10.1142/9789814520652_0038
Radioembolization for Hepatocellular Carcinoma Using Yttrium-90 Microspheres: A Comprehensive Report of Long-term Outcomes, Gastroenterology, vol.138, issue.1, pp.52-64, 2010. ,
DOI : 10.1053/j.gastro.2009.09.006
A new generation of anticancer, drug-loaded, colloidal vectors reverses multidrug resistance in glioma and reduces tumor progression in rats, Molecular Cancer Therapeutics, vol.5, issue.7, pp.1710-1722, 2006. ,
DOI : 10.1158/1535-7163.MCT-06-0289
URL : https://hal.archives-ouvertes.fr/hal-00358958
Pegylated Nanocapsules Produced by an Organic Solvent-Free Method: Evaluation of their Stealth Properties, Pharmaceutical Research, vol.134, issue.109, pp.2190-2199, 2006. ,
DOI : 10.1007/s11095-006-9061-y
Brain tumor epidemiology: consensus from the Brain Tumor Epidemiology Consortium, Cancer, vol.113, pp.1953-1968, 2008. ,
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma, N Engl J Med, vol.352, pp.987-996, 2005. ,
Chemotherapy delivery issues in central nervous system malignancy: a reality check, J Clin Oncol, vol.25, pp.2295-2305, 2007. ,
Local injection of the 90Y- labelled peptidic vector DOTATOC to control gliomas of WHO grades II and III: an extended pilot study, Eur J Nucl Med Mol Imaging, vol.29, pp.486-493, 2002. ,
Novel human IgG2b/murine chimeric antitenascin monoclonal antibody construct radiolabeled with 131I and administered into the surgically created resection cavity of patients with malignant glioma: phase I trial results, 2006. ,
Phase I singledose study of intracavitary-administered Nimotuzumab labeled with 188 Re in adult recurrent high-grade glioma, Cancer Biol Ther, vol.7, pp.333-339, 2008. ,
Nanotechnological applications in medicine, Current Opinion in Biotechnology, vol.18, issue.1, pp.26-30, 2007. ,
DOI : 10.1016/j.copbio.2007.01.006
A novel phase inversionbased process for the preparation of lipid nanocarriers, Pharmaceutical Research, vol.19, issue.6, pp.875-880, 2002. ,
DOI : 10.1023/A:1016121319668
Lipid nanocapsules: ready-to-use nanovectors for the aerosol delivery of paclitaxel, Eur J Pharm Biopharm, vol.73, pp.239-246, 2009. ,
In vivo evaluation of lipid nanocapsules as a promising colloidal carrier for paclitaxel, Int J Pharm, vol.344, pp.143-149, 2007. ,
URL : https://hal.archives-ouvertes.fr/inserm-00258366
The encapsulation of DNA molecules within biomimetic lipid nanocapsules, Biomaterials, vol.30, pp.3197-3204, 2009. ,
A new generation of anticancer, drug-loaded, colloidal vectors reverses multidrug resistance in glioma and reduces tumor progression in rats, Molecular Cancer Therapeutics, vol.5, issue.7, pp.1710-1722, 2006. ,
DOI : 10.1158/1535-7163.MCT-06-0289
URL : https://hal.archives-ouvertes.fr/hal-00358958
Etoposide nanocarriers suppress glioma cell growth by intracellular drug delivery and simultaneous P-glycoprotein inhibition, Journal of Controlled Release, vol.112, issue.2, pp.208-213, 2006. ,
DOI : 10.1016/j.jconrel.2006.02.014
Reciprocal competition between lipid nanocapsules and P-gp for paclitaxel transport across Caco-2 cells, European Journal of Pharmaceutical Sciences, vol.40, issue.5, pp.422-429, 2010. ,
DOI : 10.1016/j.ejps.2010.04.015
The importance of endo-lysosomal escape with lipid nanocapsules for drug subcellular bioavailability, Biomaterials, vol.31, issue.29, pp.7542-7554, 2010. ,
DOI : 10.1016/j.biomaterials.2010.06.024
188Re-loaded lipid nanocapsules as a promising radiopharmaceutical carrier for internal radiotherapy of malignant gliomas, European Journal of Nuclear Medicine and Molecular Imaging, vol.112, issue.10, pp.1838-1846, 2008. ,
DOI : 10.1007/s00259-008-0735-z
URL : https://hal.archives-ouvertes.fr/inserm-00343438
In vivo evaluation of intracellular drug-nanocarriers infused into intracranial tumours by convection-enhanced delivery: distribution and radiosensitisation efficacy, Journal of Neuro-Oncology, vol.28, issue.2, pp.195-205 ,
DOI : 10.1007/s11060-009-0012-4
Manganese superoxide dismutase-mediated gene expression in radiation-induced adaptive responses, 2003. ,
Non-targeted bystander effects induced by ionizing radiation, Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, vol.616, issue.1-2, pp.159-164, 2007. ,
DOI : 10.1016/j.mrfmmm.2006.11.009
IL-8 and IL-6 bystander signalling in human glioblastoma cells exposed to gamma radiation, Anticancer Res, vol.30, pp.2769-2772, 2010. ,
Cell death modalities: classification and pathophysiological implications, Cell Death and Differentiation, vol.94, issue.7, pp.1237-1243, 2007. ,
DOI : 10.1038/sj.cdd.4402148
Systemic effects of local radiotherapy, The Lancet Oncology, vol.10, issue.7, pp.718-726, 2009. ,
DOI : 10.1016/S1470-2045(09)70082-8
Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy, Nat Med, vol.13, pp.1050-1059, 2007. ,
URL : https://hal.archives-ouvertes.fr/hal-00316924
Indirect Macrophage Responses to Ionizing Radiation: Implications for Genotype-Dependent Bystander Signaling, Cancer Research, vol.68, issue.2, pp.450-456, 2008. ,
DOI : 10.1158/0008-5472.CAN-07-3050
Dendritic cells resurrect antigens from dead cells, Trends in Immunology, vol.22, issue.3, pp.141-148, 2001. ,
DOI : 10.1016/S1471-4906(01)01860-9
Induction of acute phase gene expression by brain irradiation, International Journal of Radiation Oncology*Biology*Physics, vol.33, issue.3, pp.619-626, 1995. ,
DOI : 10.1016/0360-3016(95)00279-8
Rapid induction of cytokine gene expression in the lung after single and fractionated doses of radiation, Int J Radiat Biol, vol.75, pp.1421-1427, 1999. ,
Induction of the Expression of the Interleukin-1b Gene in Mouse Spleen by Ionizing Radiation, Radiation Research, vol.133, issue.3, pp.321-326, 1993. ,
DOI : 10.2307/3578216
A sense of danger from radiation Radiation therapy and Toll-like receptor signaling: implications for the treatment of cancer, Radiat Res Oncogene, vol.162, issue.27, pp.1-19200, 2004. ,
The effect of the physical form of poly(lactic-co-glycolic acid) carriers on the humoral immune response to co-delivered antigen, Biomaterials, vol.26, issue.16, pp.2991-2999, 2005. ,
DOI : 10.1016/j.biomaterials.2004.08.023
The adjuvant activity of nonionic block polymer surfactants. I. The role of hydrophile-lipophile balance, J Immunol, vol.127, pp.1244-1250, 1981. ,
Targeting dendritic cells with biomaterials: developing the next generation of vaccines, Trends in Immunology, vol.27, issue.12, pp.573-579, 2006. ,
DOI : 10.1016/j.it.2006.10.005
Poly(lactic-co-glycolic acid) enhances maturation of human monocyte-derived dendritic cells, Journal of Biomedical Materials Research, vol.2, issue.1, pp.45-54, 2004. ,
DOI : 10.1002/jbm.a.30131
A kit formulation for the labelling of lipiodol with generator-produced188Re, Journal of Labelled Compounds and Radiopharmaceuticals, vol.9, issue.12, pp.857-867, 2004. ,
DOI : 10.1002/jlcr.863
Combination of intracranial temozolomide with intracranial carmustine improves survival when compared with either treatment alone in a rodent glioma model Chemotherapy and immunotherapy of malignant glioma: molecular mechanisms and clinical perspectives, Neurosurgery Cell Mol Life Sci, vol.66, issue.56, pp.530-537, 1999. ,
Innate and Adaptive Autoimmunity Directed to the Central Nervous System, Neuron, vol.64, issue.1, pp.123-132, 2009. ,
DOI : 10.1016/j.neuron.2009.09.015
Immune Influence on Adult Neural Stem Cell Regulation and Function, Neuron, vol.64, issue.1, pp.79-92, 2009. ,
DOI : 10.1016/j.neuron.2009.08.038
URL : http://doi.org/10.1016/j.neuron.2009.08.038
Is Tumor Growth Sustained by Rare Cancer Stem Cells or Dominant Clones?, Cancer Research, vol.68, issue.11, pp.4018-4021, 2008. ,
DOI : 10.1158/0008-5472.CAN-07-6334
URL : http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.465.7556
Cancer Stem Cells and Radiotherapy: New Insights Into Tumor Radioresistance, JNCI Journal of the National Cancer Institute, vol.98, issue.24, pp.1755-1757, 2006. ,
DOI : 10.1093/jnci/djj505
URL : http://jnci.oxfordjournals.org/cgi/content/short/98/24/1755
Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma, Cancer Res, vol.64, pp.7011-7021, 2004. ,
Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines, Cancer Cell, vol.9, pp.391-403, 2006. ,
Identification of human brain tumour initiating cells, Nature, vol.432, pp.396-401, 2004. ,
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response, Nature, vol.8, issue.7120, pp.756-760, 2006. ,
DOI : 10.1038/nature05236
Tumour stem cells and drug resistance, Nature Reviews Cancer, vol.22, issue.4, pp.275-284, 2005. ,
DOI : 10.1006/gyno.2002.6762
Radiation-induced apoptosis, Cell and Tissue Research, vol.301, issue.1, pp.133-142, 2000. ,
DOI : 10.1007/s004410000188
Possible Future Issues in the Treatment of Glioblastomas: Special Emphasis on Cell Migration and the Resistance of Migrating Glioblastoma Cells to Apoptosis, Journal of Clinical Oncology, vol.23, issue.10, pp.2411-2422, 2005. ,
DOI : 10.1200/JCO.2005.03.089
In vivo evaluation of intracellular drug-nanocarriers infused into intracranial tumours by convection-enhanced delivery: distribution and radiosensitisation efficacy, Journal of Neuro-Oncology, vol.28, issue.2, pp.195-205, 2010. ,
DOI : 10.1007/s11060-009-0012-4
Inflammatory and Anti-glioma Effects of an Adenovirus Expressing Human Soluble Fms-like Tyrosine Kinase 3 Ligand (hsFlt3L): Treatment with hsFlt3L Inhibits Intracranial Glioma Progression, Molecular Therapy, vol.10, issue.6, pp.1071-84, 2004. ,
DOI : 10.1016/j.ymthe.2004.08.025
Rat brain tumor models in experimental neuro-oncology: the C6, 9L, T9, RG2, F98, BT4C, RT-2 and CNS-1 gliomas, Journal of Neuro-Oncology, vol.10, issue.Suppl 1, pp.299-312, 2009. ,
DOI : 10.1007/s11060-009-9875-7
Epidermal growth factor ligand-independent, unregulated, cell-transforming potential of a naturally occurring human mutant EGFRvIII gene, Cell Growth Differ, vol.6, issue.10, pp.1251-1260, 1995. ,
Characterization of the epidermal growth factor receptor in human glioma cell lines and xenografts, Cancer Res, vol.50, issue.24, pp.8017-8039, 1990. ,
Constitutive EGFR signaling confers a motile phenotype to neural stem cells, Molecular and Cellular Neuroscience, vol.24, issue.4, pp.1116-1146, 2003. ,
DOI : 10.1016/j.mcn.2003.09.011
Effects of syngeneic cellular vaccinations alone or in combination with GM-CSF on the weakly immunogenic F98 glioma model, Journal of Neuro-Oncology, vol.50, issue.1, pp.9-17, 2006. ,
DOI : 10.1007/s11060-005-9115-8
Diversity and frequency of epidermal growth factor receptor mutations in human glioblastomas, Cancer Res, vol.60, issue.5, pp.1383-1390, 2000. ,
Prognostic Effect of Epidermal Growth Factor Receptor and EGFRvIII in Glioblastoma Multiforme Patients, Clinical Cancer Research, vol.11, issue.4, pp.1462-1468, 2005. ,
DOI : 10.1158/1078-0432.CCR-04-1737
The Enhanced Tumorigenic Activity of a Mutant Epidermal Growth Factor Receptor Common in Human Cancers Is Mediated by Threshold Levels of Constitutive Tyrosine Phosphorylation and Unattenuated Signaling, Journal of Biological Chemistry, vol.272, issue.5, pp.2927-2962, 1997. ,
DOI : 10.1074/jbc.272.5.2927
Inhibition of the Type III Epidermal Growth Factor Receptor Variant Mutant Receptor by Dominant-Negative EGFR-CD533 Enhances Malignant Glioma Cell Radiosensitivity, Clinical Cancer Research, vol.10, issue.19, pp.6732-6775, 2004. ,
DOI : 10.1158/1078-0432.CCR-04-0393
EGFRvIII-mediated radioresistance through a strong cytoprotective response, Oncogene, vol.22, issue.36, pp.5545-53, 2003. ,
DOI : 10.1038/sj.onc.1206788
Radiation-induced activation of a common variant of EGFR confers enhanced radioresistance, Radiotherapy and Oncology, vol.72, issue.3, pp.267-73, 2004. ,
DOI : 10.1016/j.radonc.2004.07.004
Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin, Nature, vol.4, issue.5998, pp.144-151, 1985. ,
DOI : 10.1038/313144a0
Cloning of the human homologue of the murine flt3 ligand: a growth factor for early hematopoietic progenitor cells, Blood, vol.83, issue.10, pp.2795-801, 1994. ,
Flt3 ligand induces tumor regression and antitumor immune responses in vivo, Nature Medicine, vol.9, issue.6, pp.625-656, 1997. ,
DOI : 10.1016/0925-5710(95)00389-A
Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified, Journal of Experimental Medicine, vol.184, issue.5, pp.1953-62, 1996. ,
DOI : 10.1084/jem.184.5.1953
Expression of Oncogenic Epidermal Growth Factor Receptor Family Kinases Induces Paclitaxel Resistance and Alters ??-Tubulin Isotype Expression, Journal of Biological Chemistry, vol.275, issue.23, pp.17358-63, 2000. ,
DOI : 10.1074/jbc.M000966200
B7.1 expression by the weakly immunogenic F98 rat glioma does not enhance immunogenicity, Gene Therapy, vol.7, issue.12, pp.993-1002, 2000. ,
DOI : 10.1038/sj.gt.3301209
Expression of a naturally occurring constitutively active variant of the epidermal growth factor receptor in mouse fibroblasts increases motility, International Journal of Cancer, vol.7, issue.5, pp.643-53, 2004. ,
DOI : 10.1002/ijc.11566
Chemotherapy and immunotherapy of malignant glioma: molecular mechanisms and clinical perspectives, Cellular and Molecular Life Sciences (CMLS), vol.56, issue.5-6, pp.5-6, 1999. ,
DOI : 10.1007/s000180050447
Tumor-specific immunotherapy targeting the EGFRvIII mutation in patients with malignant glioma, Seminars in Immunology, vol.20, issue.5, pp.267-75, 2008. ,
DOI : 10.1016/j.smim.2008.04.001
Dendritic Cell Development in Culture from Thymic Precursor Cells in the Absence of Granulocyte/Macrophage Colony-stimulating Factor, Journal of Experimental Medicine, vol.184, issue.6, 1996. ,
DOI : 10.1084/jem.184.6.2185
Phenotype and functional activity of tumor-infiltrating lymphocytes isolated from immunogenic and nonimmunogenic rat brain tumors, Cancer Res, vol.51, issue.9, pp.2373-2381, 1991. ,
Structural alterations of the epidermal growth factor receptor gene in human gliomas., Proceedings of the National Academy of Sciences, vol.89, issue.7, pp.2965-2974, 1992. ,
DOI : 10.1073/pnas.89.7.2965
Is Tumor Growth Sustained by Rare Cancer Stem Cells or Dominant Clones?, Cancer Research, vol.68, issue.11, pp.4018-4039, 2008. ,
DOI : 10.1158/0008-5472.CAN-07-6334
URL : http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.465.7556
188Re-loaded lipid nanocapsules as a promising radiopharmaceutical carrier for internal radiotherapy of malignant gliomas, European Journal of Nuclear Medicine and Molecular Imaging, vol.112, issue.10, pp.1838-1884, 2008. ,
DOI : 10.1007/s00259-008-0735-z
URL : https://hal.archives-ouvertes.fr/inserm-00343438
Convection-enhanced delivery of nanocarriers for the treatment of brain tumors, Biomaterials, vol.30, issue.12, pp.2302-2320, 2009. ,
DOI : 10.1016/j.biomaterials.2009.01.003
Toll-like receptor 4???dependent contribution of the immune system to anticancer chemotherapy and radiotherapy, Nature Medicine, vol.289, issue.9, pp.1050-1059, 2007. ,
DOI : 10.1038/nm1622
URL : https://hal.archives-ouvertes.fr/hal-00316924
99mTc/188Re-labelled lipid nanocapsules as promising radiotracers for imaging and therapy: formulation and biodistribution, European Journal of Nuclear Medicine and Molecular Imaging, vol.242, issue.5, pp.602-609, 2006. ,
DOI : 10.1007/s00259-005-0007-0
URL : http://doi.org/10.1007/s00259-005-0007-0
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response, Nature, vol.8, issue.7120, pp.756-60, 2006. ,
DOI : 10.1038/nature05236
Rat brain tumor models in experimental neuro-oncology: the C6, 9L, T9, RG2, F98, BT4C, RT-2 and CNS-1 gliomas, Journal of Neuro-Oncology, vol.10, issue.Suppl 1, pp.299-312, 2009. ,
DOI : 10.1007/s11060-009-9875-7
Iodine-131-labeled antitenascin monoclonal antibody 81C6 treatment of patients with recurrent malignant gliomas: phase I trial results., Journal of Clinical Oncology, vol.16, issue.6, pp.2202-2214, 1998. ,
DOI : 10.1200/JCO.1998.16.6.2202
Receptor radionuclide therapy with 90Y-[DOTA]0-Tyr3-octreotide (90Y-DOTATOC) in neuroendocrine tumours, European Journal of Nuclear Medicine and Molecular Imaging, vol.31, issue.7, pp.1038-1084, 2004. ,
DOI : 10.1007/s00259-004-1571-4
Nanotechnological applications in medicine, Current Opinion in Biotechnology, vol.18, issue.1, pp.26-30, 2007. ,
DOI : 10.1016/j.copbio.2007.01.006
Indirect Macrophage Responses to Ionizing Radiation: Implications for Genotype-Dependent Bystander Signaling, Cancer Research, vol.68, issue.2, pp.450-456, 2008. ,
DOI : 10.1158/0008-5472.CAN-07-3050
Treatment of nonresectable hepatocellular carcinoma with intrahepatic 90Y-microspheres, J Nucl Med, vol.41, issue.10, pp.1673-81, 2000. ,
The chemistry of rhenium and technetium as related to the use of isotopes of these elements in therapeutic and diagnostic nuclear medicine, International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology, vol.13, issue.4, pp.465-77, 1986. ,
DOI : 10.1016/0883-2897(86)90027-9
Cancer Stem Cells and Radiotherapy: New Insights Into Tumor Radioresistance, JNCI Journal of the National Cancer Institute, vol.98, issue.24, pp.1755-1762, 2006. ,
DOI : 10.1093/jnci/djj505
A new generation of anticancer, drug-loaded, colloidal vectors reverses multidrug resistance in glioma and reduces tumor progression in rats, Molecular Cancer Therapeutics, vol.5, issue.7, pp.1710-1732, 2006. ,
DOI : 10.1158/1535-7163.MCT-06-0289
URL : https://hal.archives-ouvertes.fr/hal-00358958
A novel phase inversion-based process for the preparation of lipid nanocarriers, Pharmaceutical Research, vol.19, issue.6, pp.875-80, 2002. ,
DOI : 10.1023/A:1016121319668
Rhenium-188-labeled DTPA: a new radiopharmaceutical for intravascular radiation therapy, Nuclear Medicine and Biology, vol.26, issue.8, pp.967-72, 1999. ,
DOI : 10.1016/S0969-8051(99)00074-8
X-irradiation to human malignant glioma cells enhances the cytotoxicity of autologous killer lymphocytes under specific conditions, International Journal of Radiation Oncology*Biology*Physics, vol.59, issue.5, pp.1505-1517, 2004. ,
DOI : 10.1016/j.ijrobp.2004.04.046
Yttrium-90 microspheres (TheraSphere??) treatment of unresectable hepatocellular carcinoma: Downstaging to resection, RFA and bridge to transplantation, Journal of Surgical Oncology, vol.29, issue.7, pp.572-86, 2006. ,
DOI : 10.1002/jso.20609
Selective internal radiation therapy for nonresectable hepatocellular carcinoma with intraarterial infusion of 90yttrium microspheres, International Journal of Radiation Oncology*Biology*Physics, vol.40, issue.3, pp.583-92, 1998. ,
DOI : 10.1016/S0360-3016(97)00818-3
Locoregional regulatory peptide receptor targeting with the diffusible somatostatin analogue 90Y-labeled DOTA0-D-Phe1-Tyr3-octreotide (DOTATOC): a pilot study in human gliomas, Clin Cancer Res, vol.5, issue.5, pp.1025-1058, 1999. ,
The importance of endo-lysosomal escape with lipid nanocapsules for drug subcellular bioavailability, Biomaterials, vol.31, issue.29, pp.7542-54, 2010. ,
DOI : 10.1016/j.biomaterials.2010.06.024
Salvage Radioimmunotherapy With Murine Iodine-131???Labeled Antitenascin Monoclonal Antibody 81C6 for Patients With Recurrent Primary and Metastatic Malignant Brain Tumors: Phase II Study Results, Journal of Clinical Oncology, vol.24, issue.1, pp.115-137, 2006. ,
DOI : 10.1200/JCO.2005.03.4082
Cancer Stem Cells in Radiation Resistance, Cancer Research, vol.67, issue.19, pp.8980-8984, 2007. ,
DOI : 10.1158/0008-5472.CAN-07-0895
Comparative Analysis of DNA Repair in Stem and Nonstem Glioma Cell Cultures, Molecular Cancer Research, vol.7, issue.3, pp.383-92, 2009. ,
DOI : 10.1158/1541-7786.MCR-08-0409
Chemotherapy and immunotherapy of malignant glioma: molecular mechanisms and clinical perspectives, Cellular and Molecular Life Sciences (CMLS), vol.56, issue.5-6, pp.5-6, 1999. ,
DOI : 10.1007/s000180050447
Treatment of Unresectable Hepatocellular Carcinoma with Use of 90Y Microspheres (TheraSphere): Safety, Tumor Response, and Survival, Journal of Vascular and Interventional Radiology, vol.16, issue.12, pp.1627-1666, 2005. ,
DOI : 10.1097/01.RVI.0000184594.01661.81
Effect of Brain-Derived Neurotrophic Factor Treatment and Forced Arm Use on Functional Motor Recovery After Small Cortical Ischemia, Stroke, vol.35, issue.4, pp.992-999, 2004. ,
DOI : 10.1161/01.STR.0000119754.85848.0D
Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma, New England Journal of Medicine, vol.352, issue.10, pp.987-96, 2005. ,
DOI : 10.1056/NEJMoa043330
External irradiation models for intracranial 9L glioma studies, Journal of Experimental & Clinical Cancer Research, vol.29, issue.1, p.142, 2010. ,
DOI : 10.1186/1756-9966-29-142
URL : http://doi.org/10.1186/1756-9966-29-142
In vivo evaluation of intracellular drug-nanocarriers infused into intracranial tumours by convection-enhanced delivery: distribution and radiosensitisation efficacy, Journal of Neuro-Oncology, vol.28, issue.2, 2009. ,
DOI : 10.1007/s11060-009-0012-4
Technologies et Ingienerie de la Santé (5 semaines): - " Evaluation de la réponse immunitaire périphérique après radiothérapie interne nanovectorisée dans un modèle de gliome, Encadrement: * Encadrement d'étudiants en Master 1 Sciences Dosage des cytokines Interleukine-2 et Interferon-? après radiothérapie interne dans un modèle de gliome chez le rat ,
Animal (14 semaines): - " Caractérisation de la réponse immunitaire induite par la radiothérapie interne nanovectorisée dans un modèle de gliome, Etude de la stimulation du système immunitaire après radiothérapie interne nanovectorisée associée à une vaccination dans un modèle de gliome ,
Epub Nov 12 -The therapeutic potential of human multipotent mesenchymal stromal cells combined with pharmacologically active microcarriers transplanted in hemi-parkinsonian rats, pp.1560-732010 ,
Radiothérapie interne fractionnée à l'aide des nanocapsules lipidiques chargées en rhénium-188 dans un modèle de glioblastome de rat -47ème, 2009. ,
Internal radiation with 188Re-loaded lipid nanocapsules in a rat hepatocellular carcinoma -1srt TARCC international Workshop on targeted radionuclide therapyAdvances in targeted radionuclide therapy, 2009. ,
Hindré F. -Injection intra-artérielle de nanocapsules lipidiques chargées en rhénium-188, pour le traitement du carcinome hépatocellulaire chez le rat -47ème Colloque de Médecine Nucléaire de Langue Française, pp.9-12, 2009. ,
Stereotaxic injections of 188-Re loaded nanocapsules as fractionated internal radioation in a rat glioblastoma model -1srt TARCC international Workshop on targeted radionuclide therapyAdvances in targeted radionuclide therapy, 2009. ,
-Intra-arterial injection of lipid nanocapsules loaded with rhenium-188 for the radiotherapy of hepatocellular carcinomas in rats. ? New trends in Molecular Imaging and Nuclear Medicine, Award « Young Investigator award, pp.14-2009 ,
URL : https://hal.archives-ouvertes.fr/hal-00443488
Hindré F. ? Administration of 188 Re-loaded nanocapsules into the hepatic artery involves neoangiogenesis alterations in a rat hepatocellular carcinoma model. -Targeting and Imaging of the Tumor Microenvironment from the 23rd to 26th of, 2009. ,
Hindré F. ? Evaluation of immune responses after nanovectorized internal radiotherapy for glioblastomas, World Molecular Congress, 2010. ,
Hindré F. ? Evaluation of immune responses after nanovectorized internal radiotherapy for glioblastomas. ? Biology of ionizing radiation from the 22nd to 25th of, 2010. ,
Hindré F. ? Nanovectorized internal radiation therapy in a glioblastoma rat model. ? EANM'10, Annual Congress of the European Association of Nuclear Medicine, pp.9-13, 2010. ,