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. Hz, 40 (s, 2 H, H-6), 6.04 (s, 2 H, H-8a), 6.15 (s, 2 H, pp.50-53

. Hz, 52-3.63 (m, 1 H, H-7), 4.88 (d, J 6-7 = 7.0 Hz, 0, p.338

. Hz, 41 (ddd, J 4eq-2eq = 1.5 Hz, 1 H, H-4eq), 3.90 (d, J 1'a-1'b = 13.5 Hz, 1 H, H-1'a), 3.92 (s, 3 H, CH 3 ), 4.04 (d, 1 H, H-1'b), pp.31-35

. Hz, 50 (d, J 2"-3" = 8.5 Hz, p.9

. Hz, 94 (s, 3 H, CH 3 ), 4.48 (d, J 2ax-2eq = 10.5 Hz, 1 H, H-2ax), 4.60 (d, J 6ax-5 = 10, Hz, 1 H, H-6ax), 4.69 (dd, p.9

J. Hz, 30 (dd, J 10a-10b = 14.0 Hz, J 10a-11 = 6.5 Hz, 2 H, H-10a), 3.38 (dd, pp.4-45, 2002.

J. Hz, 19 (dd, J 4ax-4eq = 13.5 Hz, J 4ax- 5eq = 3.5 Hz, 1.5 H, H-4ax major), 3.35-3.89 (m, 256 H, PEG backbone, H-4eq minor, H-4ax minor, H-4eq major, pp.4-48

. Hz, 25 (dd, J 3'e-2' = 9.5 Hz, J 3'e-3'z = 1.0 Hz, 2 H, H-3'e), 5.35 (dd, J 3'z-2' = 15 Hz, pp.77-82

. Hz, 58 (dm, 1 H, H-4eq), 3.61 (dd, J 1'a-1'b = 13.5 Hz, J 1'a-2' = 6.5 Hz, 1 H, H-1'a), 3.65 (dd, J 1'b-2' = 6.5 Hz, pp.3-94

. Hz, 32 (dd, J 4ax-4eq = 13

. Hz, 1.5 Hz, 1 H, H-4eq), 3.53 (dd, J 1'b-2' = 6.5 Hz, 1 H, H-1'b), 3.95 (s, 3 H, CH 3, pp.50-54

H. Esi, Compound 37c To 1 mL solution of MeONa in MeOH (0.1 M), compound 37b (550 mg, 0.21 mmol), was added. The reaction mixture was stirred at room temperature for 3 hours, mL of CH 3 COOH in MeOH (0.1 M) was added and the mixture was stirred at room temperature for 10 min

A. Ether, :3) to give 37c (45 mg, 37 %) as white foam (m, °C), and 37d (24 mg, 20 %) as colorless oil, pp.138-140

J. Hz, 64 (ddd, J 4eq-2eq(W) = 2.0 Hz, 1 H, H-4eq), 3.65 (dd, J 1'a-1'b = 17.0 Hz, 1 H, H-1'a), 3.70 (dd, 1 H, H-1'b), 3.94 (s, 3 H, CH 3, pp.4-74

J. Hz, 27 (dd, J 4ax-4eq = 13.5 Hz, J 4ax-5eq = 3.5 Hz, 1.5 H, H-4ax major), 3.37-3.44 (m, 2 H, H-4ax minor, H-4eq minor), 3.49 (dm, 1, pp.3-53

H. Hz and H. , 1.5 Hz 140 (d, J 3'-4' = 8.0 Hz, 0.5 H, H-3' minor), 7.50 (d, J 2, pp.4-86, 2002.

M. Ms, Compound 38c To 2 mL solution of MeONa in MeOH (0.1 M), compound 38b (1.36 g, 0.5 mmol), was added. The reaction mixture was stirred at room temperature for 3 hours, mL of CH 3 COOH in MeOH (0.1 M) was added and the mixture was stirred at room temperature for 10 min

. Hz, 48 (dm, 1 H, H-4eq), 3.89 (s, 3 H, CH 3

H. Hz, 4.24 (d, 1 H, H-1'b), 4.41 (d, J 2ax-2eq = 10, Hz, vol.1, pp.4-72

. Hz, 34-3.44 (m, 2 H, H-4ax, H-4eq), 3.91 (s, 3 H, CH 3