milieu LB, induction par 0,1mM IPTG, 20°C, sur la nuit) Pour contrôle négatif, des bactéries C43(DE3) transformées avec le même vecteur ne contenant pas l'ADNc codant pour hAAC1 (vecteur vide) ont été utilisées ,
High Sensitivity Identification of Membrane Proteins by MALDI TOF-MASS Spectrometry Using Polystyrene Beads, Journal of Proteome Research, vol.6, issue.4, pp.1595-1602, 2007. ,
DOI : 10.1021/pr0606272
X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation, Nature, vol.3, issue.7225, pp.111-114, 2009. ,
DOI : 10.1523/JNEUROSCI.3467-06.2006
A sequence related to a DNA recognition element is essential for the inhibition by nucleotides of proton transport through the mitochondrial uncoupling protein, 1994. ,
Complete cDNA-derived amino acid sequence of rat brown fat uncoupling protein, J Biol Chem, vol.261, pp.1487-1490, 1986. ,
Chemical, immunological, enzymatic, and genetic approaches to studying the arrangement of the peptide chain of the ADP/ATP carrier in the mitochondrial membrane, Journal of Bioenergetics and Biomembranes, vol.17, issue.5, pp.459-472, 1993. ,
DOI : 10.1007/BF01108403
On the Mechanism of Mitochondrial Uncoupling Protein 1 Function, Journal of Biological Chemistry, vol.281, issue.4, pp.2114-2119, 2006. ,
DOI : 10.1074/jbc.M511575200
The binding of atractyloside and oligomycin to liver mitochondria, Biochimica et Biophysica Acta (BBA) - General Subjects, vol.100, issue.1, pp.1-12, 1965. ,
DOI : 10.1016/0304-4165(65)90421-6
Effects of Atractyloside and Oligomycin on Magnesium-stimulated Adenosine Triphosphatase and on Adenosine Triphosphate-induced Contraction of Swollen Mitochondria, Nature, vol.236, issue.4854, 1962. ,
DOI : 10.1016/S0003-2670(00)89983-3
Electrical currents associated with nucleotide transport by the reconstituted mitochondrial ADP/ATP carrier., Proceedings of the National Academy of Sciences, vol.93, issue.2, pp.664-668, 1996. ,
DOI : 10.1073/pnas.93.2.664
The reconstituted ADP/ATP carrier can mediate H+ transport by free fatty acids, which is further stimulated by mersalyl, J Biol Chem, vol.269, pp.27329-27336, 1994. ,
Identification of serine phosphorylation in mitochondrial uncoupling protein 1, Biochimica et Biophysica Acta (BBA) - Bioenergetics, vol.1777, issue.7-8, pp.1060-1065, 2008. ,
DOI : 10.1016/j.bbabio.2008.04.030
N-terminal transmembrane domain of the SUR controls trafficking and gating of Kir6 channel subunits, The EMBO Journal, vol.22, issue.15, pp.3833-3843, 2003. ,
DOI : 10.1093/emboj/cdg376
Importing Mitochondrial Proteins: Machineries and Mechanisms, Cell, vol.138, issue.4, pp.628-644, 2009. ,
DOI : 10.1016/j.cell.2009.08.005
URL : http://doi.org/10.1016/j.cell.2009.08.005
Crystallization of the bovine ADP/ATP carrier is critically dependent upon the detergent-to-protein ratio, Acta Crystallographica Section D Biological Crystallography, vol.59, issue.12, pp.2353-2355, 2003. ,
DOI : 10.1107/S0907444903020699
Mapping of the nucleotide-binding sites in the ADP/ATP carrier of beef heart mitochondria by photolabeling with 2-azido[.alpha.-32P]adenosine diphosphate, Biochemistry, vol.27, issue.14, pp.5141-5149, 1988. ,
DOI : 10.1021/bi00414a029
New tensio-active molecules stabilize a human G protein-coupled receptor in solution, FEBS Letters, vol.280, issue.10, pp.1944-1950, 2007. ,
DOI : 10.1016/j.febslet.2007.03.091
URL : https://hal.archives-ouvertes.fr/inserm-00868640
Valine 181 is critical for the nucleotide exchange activity of human mitochondrial ADP/ATP carriers in yeast, Biochemistry, vol.44, pp.4342-4348, 2005. ,
URL : https://hal.archives-ouvertes.fr/hal-00376047
Translocation of mitochondrial inner-membrane proteins: conformation matters, Trends in Biochemical Sciences, vol.31, issue.5, pp.259-267, 2006. ,
DOI : 10.1016/j.tibs.2006.03.006
Binding of ADP in the Mitochondrial ADP/ATP Carrier Is Driven by an Electrostatic Funnel, Journal of the American Chemical Society, vol.130, issue.38, pp.12725-12733, 2008. ,
DOI : 10.1021/ja8033087
A fourth ADP/ATP carrier isoform in man: identification, bacterial expression, functional characterization and tissue distribution, FEBS Letters, vol.41, issue.3, pp.633-637, 2005. ,
DOI : 10.1016/j.febslet.2004.12.034
??xchange entre adenine-nucleotides extra- et intramitochondriaux, Biochimica et Biophysica Acta (BBA) - General Subjects, vol.107, issue.1, pp.184-188, 1965. ,
DOI : 10.1016/0304-4165(65)90419-8
Relationship between the energy cost of ATP transport and ATP synthesis in mitochondria, Biochimica et Biophysica Acta (BBA) - Bioenergetics, vol.637, issue.2, pp.217-223, 1981. ,
DOI : 10.1016/0005-2728(81)90160-2
Kinetic Mechanism of the Exchanges Catalysed by the Adenine-Nucleotide Carrier, European Journal of Biochemistry, vol.254, issue.1, pp.1-6, 1980. ,
DOI : 10.1111/j.1432-1033.1980.tb05990.x
Bacterial expression of a eukaryotic membrane protein in fusion to various Mistic orthologs, Protein Expression and Purification, vol.68, issue.1, pp.28-33, 2009. ,
DOI : 10.1016/j.pep.2009.06.007
Coenzyme Q is an obligatory cofactor for uncoupling protein function, Nature, vol.408, pp.609-613, 2000. ,
A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling, The EMBO Journal, vol.22, issue.16, pp.4103-4110, 2003. ,
DOI : 10.1093/emboj/cdg412
Superoxide activates mitochondrial uncoupling proteins, Nature, vol.415, issue.6867, pp.96-99, 2002. ,
DOI : 10.1038/415096a
In the uncoupling protein from brown adipose tissue the C-terminus protrudes to the c-side of the membrane as shown by tryptic cleavage, FEBS Letters, vol.6, issue.1, pp.166-170, 1987. ,
DOI : 10.1016/0014-5793(87)80572-0
Ubiquinone is not required for proton conductance by uncoupling protein 1 in yeast mitochondria, Biochemical Journal, vol.379, issue.2, pp.309-315, 2004. ,
DOI : 10.1042/bj20031682
Cloning of the hsp70 (dnaK) genes from Rhizobium meliloti and Pseudomonas cepacia: phylogenetic analyses of mitochondrial origin based on a highly conserved protein sequence., Journal of Bacteriology, vol.176, issue.24, pp.7748-7753, 1994. ,
DOI : 10.1128/jb.176.24.7748-7753.1994
Abundant bacterial expression and reconstitution of an intrinsic membrane-transport protein from bovine mitochondria, Biochemical Journal, vol.294, issue.1, pp.293-299, 1993. ,
DOI : 10.1042/bj2940293
Mechanism of uncoupling protein action, Biochemical Society Transactions, vol.29, issue.6, pp.803-806, 2001. ,
DOI : 10.1042/bst0290803
How do uncoupling proteins uncouple?, Biochimica et Biophysica Acta (BBA) - Bioenergetics, vol.1459, issue.2-3, pp.383-389, 2000. ,
DOI : 10.1016/S0005-2728(00)00175-4
URL : http://doi.org/10.1016/s0005-2728(00)00175-4
On the Mechanism of Fatty Acid-induced Proton Transport by Mitochondrial Uncoupling Protein, Journal of Biological Chemistry, vol.271, issue.5, pp.2615-2620, 1996. ,
DOI : 10.1074/jbc.271.5.2615
Structure-function studies of adenine nucleotide transport in mitochondria. II. Biochemical analysis of distinct AAC1 and AAC2 proteins in yeast, J Biol Chem, vol.265, pp.14202-14208, 1990. ,
Integration of PCR fragments at any specific site within cloning vectors without the use of restriction enzymes and DNA ligase, 2001. ,
Structural and functional study of a conserved region in the uncoupling protein UCP1: the three matrix loops are involved in the control of transport, J Mol Biol, vol.292, pp.137-149, 1999. ,
Kinetics of Electrogenic Transport by the ADP/ATP Carrier, Biophysical Journal, vol.77, issue.2, pp.714-726, 1999. ,
DOI : 10.1016/S0006-3495(99)76926-2
In Vitro Multimerization and Membrane Insertion of Bacterial Outer Membrane Secretin PulD, Journal of Molecular Biology, vol.382, issue.1, pp.13-23, 2008. ,
DOI : 10.1016/j.jmb.2008.06.055
membrane reveals different biochemical characteristics for plants, mammals and anaerobic chytrids, European Journal of Biochemistry, vol.149, issue.13, pp.3172-3181, 2002. ,
DOI : 10.1046/j.1432-1033.2002.02991.x
Expression of the bovine heart mitochondrial ADP/ATP carrier in yeast mitochondria: significantly enhanced expression by replacement of the N-terminal region of the bovine carrier by the corresponding regions of the yeast carriers, Biochimica et Biophysica Acta (BBA) - Bioenergetics, vol.1409, issue.3, pp.113-124, 1999. ,
DOI : 10.1016/S0005-2728(98)00155-8
Brown-Adipose-Tissue Mitochondria: Photoaffinity Labelling of the Regulatory Site of Energy Dissipation, European Journal of Biochemistry, vol.67, issue.2, pp.515-521, 1978. ,
DOI : 10.1016/0014-5793(77)80169-5
Expression of the Mitochondrial ADP/ATP Carrier in Escherichia coli. RENATURATION, RECONSTITUTION, AND THE EFFECT OF MUTATIONS ON 10 POSITIVE RESIDUES, Journal of Biological Chemistry, vol.276, issue.15, pp.11499-11506, 2001. ,
DOI : 10.1074/jbc.M010586200
Binding of fatty acids to the uncoupling protein from brown adipose tissue mitochondria, Archives of Biochemistry and Biophysics, vol.412, issue.1, pp.142-146, 2003. ,
DOI : 10.1016/S0003-9861(03)00031-6
Fluorescent Nucleotide Derivatives as Specific Probes for the Uncoupling Protein: Thermodynamics and Kinetics of Binding and the Control by pH, Biochemistry, vol.34, issue.1, pp.349-360, 1995. ,
DOI : 10.1021/bi00001a043
Slow-phase Kinetics of Nucleotide Binding to the Uncoupling Protein from Brown Adipose Tissue Mitochondria, Journal of Biological Chemistry, vol.273, issue.2, pp.859-864, 1998. ,
DOI : 10.1074/jbc.273.2.859
Reconstitution of Recombinant Uncoupling Proteins: UCP1, -2, AND -3 HAVE SIMILAR AFFINITIES FOR ATP AND ARE UNAFFECTED BY COENZYME Q10, Journal of Biological Chemistry, vol.278, issue.28, pp.25825-25831, 2003. ,
DOI : 10.1074/jbc.M302126200
A CD study of uncoupling protein-1 and its transmembrane and matrix-loop domains, Biochemical Journal, vol.411, issue.3, pp.593-603, 2008. ,
DOI : 10.1042/BJ20071326
Reconstitution of the uncoupling protein of brown adipose tissue mitochondria. Demonstration of GDP-sensitive halide anion uniport, J Biol Chem, vol.265, pp.19296-19302, 1990. ,
New substrates and competitive inhibitors of the Cl-translocating pathway of the uncoupling protein of brown adipose tissue mitochondria, J Biol Chem, vol.265, pp.19303-19311, 1990. ,
Transport of anions and protons by the mitochondrial uncoupling protein and its regulation by nucleotides and fatty acids. A new look at old hypotheses, J Biol Chem, vol.269, pp.26184-26190, 1994. ,
Inactive fatty acids are unable to flip-flop across the lipid bilayer, FEBS Letters, vol.343, issue.2, pp.161-165, 1997. ,
DOI : 10.1016/S0014-5793(97)00334-7
Undecanesulfonate does not allosterically activate H+ uniport mediated by uncoupling protein-1 in brown adipose tissue mitochondria, The International Journal of Biochemistry & Cell Biology, vol.38, issue.11, pp.1965-1974, 2006. ,
DOI : 10.1016/j.biocel.2006.05.011
Evolutionarily Distinct Residues in the Uncoupling Protein UCP1 Are Essential for Its Characteristic Basal Proton Conductance, Journal of Molecular Biology, vol.359, issue.4, pp.1010-1022, 2006. ,
DOI : 10.1016/j.jmb.2006.04.022
Large-scale production of functional membrane proteins, Cellular and Molecular Life Sciences, vol.65, issue.11, pp.1729-1755, 2008. ,
DOI : 10.1007/s00018-008-8067-5
Functional Cell-free Synthesis of a Seven Helix Membrane Protein: In situ Insertion of Bacteriorhodopsin into Liposomes, Journal of Molecular Biology, vol.371, issue.3, pp.639-648, 2007. ,
DOI : 10.1016/j.jmb.2007.05.087
Membrane potential of mitochondria measured with an electrode sensitive to tetraphenyl phosphonium and relationship between proton electrochemical potential and phosphorylation potential in steady state, The Journal of Membrane Biology, vol.253, issue.2, pp.105-121, 1979. ,
DOI : 10.1007/BF01868720
maltose-binding protein is uncommonly effective at promoting the solubility of polypeptides to which it is fused, Protein Science, vol.12, issue.8, pp.1668-1674, 1999. ,
DOI : 10.1110/ps.8.8.1668
Application of Mistic to improving the expression and membrane integration of histidine kinase receptors from Escherichia coli, Journal of Structural and Functional Genomics, vol.6, issue.4, pp.167-172, 2007. ,
DOI : 10.1007/s10969-007-9033-4
Evaluation of detergents for the soluble expression of ??-helical and ??-barrel-type integral membrane proteins by a preparative scale individual cell-free expression system, FEBS Journal, vol.263, issue.23, pp.6024-6038, 2005. ,
DOI : 10.1111/j.1742-4658.2005.05002.x
Expression of the brown fat mitochondria uncoupling protein in Xenopus oocytes and import into mitochondrial membrane, Biochemical and Biophysical Research Communications, vol.167, issue.2, pp.784-789, 1990. ,
DOI : 10.1016/0006-291X(90)92094-G
dans : Regulation of metabolic process in mitochondria (édité par, BBA library, vol.7, pp.180-201, 1966. ,
The ADP-ATP Translocation in mitochondria, a membrane potential controlled transport, The Journal of Membrane Biology, vol.82, issue.2, pp.97-105, 1980. ,
DOI : 10.1007/BF01875961
Nucleotide binding to uncoupling protein. Mechanism of control by protonation, Biochemistry, vol.27, issue.2, pp.781-791, 1988. ,
DOI : 10.1021/bi00402a044
The ADP and ATP transport in mitochondria and its carrier, Biochimica et Biophysica Acta (BBA) - Biomembranes, vol.1778, issue.10, pp.1978-2021, 2008. ,
DOI : 10.1016/j.bbamem.2008.04.011
Cardiolipin and mitochondrial carriers, Biochimica et Biophysica Acta (BBA) - Biomembranes, vol.1788, issue.10, pp.2048-2058, 2009. ,
DOI : 10.1016/j.bbamem.2009.06.007
URL : http://doi.org/10.1016/j.bbamem.2009.06.007
The uncoupling protein dimer can form a disulfide cross-link between the mobile C-terminal SH groups, European Journal of Biochemistry, vol.211, issue.1, pp.123-131, 1989. ,
DOI : 10.1016/S0076-6879(72)25041-8
The reconstituted isolated uncoupling protein is a membrane potential driven H+ translocator, Embo J, vol.4, pp.3087-3092, 1985. ,
Genetic incativation of adenine nucleotide translocator 2 (anc2) in mouse results in cardiac insuffiency and embryonic lethality, Mitochondrion, vol.1, issue.S57, 2001. ,
Expression of the mitochondrial uncoupling protein gene from the aP2 gene promoter prevents genetic obesity., Journal of Clinical Investigation, vol.96, issue.6, pp.2914-2923, 1995. ,
DOI : 10.1172/JCI118363
The mitochondrial uncoupling-protein homologues, Nature Reviews Molecular Cell Biology, vol.12, issue.3, pp.248-261, 2005. ,
DOI : 10.1038/nrm1592
Projection Structure of the Atractyloside-inhibited Mitochondrial ADP/ATP Carrier of Saccharomyces cerevisiae, Journal of Biological Chemistry, vol.278, issue.39, pp.36985-36988, 2003. ,
DOI : 10.1074/jbc.C300304200
Mitochondrial carriers function as monomers, Biochimica et Biophysica Acta (BBA) - Bioenergetics, vol.1797, issue.6-7, 2010. ,
DOI : 10.1016/j.bbabio.2010.03.023
URL : http://doi.org/10.1016/j.bbabio.2010.03.023
Regulation of CD40 reconstitution into a liposome using different ratios of solubilized LDAO to lipids, Colloids and Surfaces B: Biointerfaces, vol.62, issue.1, pp.51-57, 2008. ,
DOI : 10.1016/j.colsurfb.2007.09.021
The uncoupling protein from brown adipose tissue mitochondria is a dimer. A hydrodynamic study, FEBS Letters, vol.20, issue.2, pp.304-306, 1980. ,
DOI : 10.1016/0014-5793(80)80614-4
Isolation of the uncoupling protein from brown adipose tissue mitochondria, FEBS Letters, vol.85, issue.2, pp.299-303, 1980. ,
DOI : 10.1016/0014-5793(80)80613-2
Characteristics of the isolated purine nucleotide binding protein from brown fat mitochondria, Biochemistry, vol.21, issue.12, pp.2950-2956, 1982. ,
DOI : 10.1021/bi00541a023
CIDE-A, a novel link between brown adipose tissue and obesity, Trends in Molecular Medicine, vol.10, issue.9, pp.434-439, 2004. ,
DOI : 10.1016/j.molmed.2004.07.005
Characterization of mitochondrial trifunctional protein and its inactivation study for medicine development, Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, vol.1784, issue.11, pp.1742-1749, 2008. ,
DOI : 10.1016/j.bbapap.2008.06.018
Structural Diversity of Mitochondria, Annals of the New York Academy of Sciences, vol.110, issue.suppl 2, pp.171-179, 2008. ,
DOI : 10.1196/annals.1427.020
Topology of the Mitochondrial Inner Membrane: Dynamics and Bioenergetic Implications, IUBMB Life (International Union of Biochemistry and Molecular Biology: Life), vol.52, issue.3-5, pp.93-100, 2001. ,
DOI : 10.1080/15216540152845885
Perspective: Does brown fat protect against diseases of aging?, Ageing Research Reviews, vol.9, issue.1, pp.69-76 ,
DOI : 10.1016/j.arr.2009.11.004
Labeling of two different regions of the nucleotide binding site of the uncoupling protein from brown adipose tissue mitochondria with two ATP-analogs, Biochemistry, vol.31, issue.43, pp.10536-10543, 1992. ,
DOI : 10.1021/bi00158a017
Antibodies selected from whole antiserum by fusion proteins as tools for the study of the topology of mitochondrial membrane proteins. Evidence that the N-terminal extremity of the sixth alpha-helix of the uncoupling protein is facing the matrix, J Biol Chem, vol.267, pp.13603-13609, 1992. ,
The topology of the brown adipose tissue mitochondrial uncoupling protein determined with antibodies against its antigenic sites revealed by a library of fusion proteins, Embo J, vol.12, pp.3739-3745, 1993. ,
Over-production of Proteins inEscherichia coli: Mutant Hosts that Allow Synthesis of some Membrane Proteins and Globular Proteins at High Levels, Journal of Molecular Biology, vol.260, issue.3, pp.289-298, 1996. ,
DOI : 10.1006/jmbi.1996.0399
Coupling of Phosphorylation to Electron and Hydrogen Transfer by a Chemi-Osmotic type of Mechanism, Nature, vol.182, issue.4784, pp.144-148, 1961. ,
DOI : 10.1002/jez.1400510306
Identification by Site-directed Mutagenesis of Three Arginines in Uncoupling Protein That Are Essential for Nucleotide Binding and Inhibition, Journal of Biological Chemistry, vol.272, issue.40, pp.24759-24762, 1997. ,
DOI : 10.1074/jbc.272.40.24759
Assessment of a high-throughput screening methodology for the measurement of purified UCP1 uncoupling activity, Analytical Biochemistry, vol.351, issue.2, pp.201-206, 2006. ,
DOI : 10.1016/j.ab.2006.01.033
URL : https://hal.archives-ouvertes.fr/hal-00136146
Functional reconstitution of rat uncoupling protein following its high level expression in yeast, J Biol Chem, vol.266, pp.11871-11875, 1991. ,
Bacterial cell-free system for high-throughput protein expression and a comparative analysis of Escherichia coli cell-free and whole cell expression systems, Protein Expression and Purification, vol.36, issue.2, pp.217-225, 2004. ,
DOI : 10.1016/j.pep.2004.04.002
A new hybrid protein for production of recombinant bacteriorhodopsin in Escherichia coli, Journal of Biotechnology, vol.147, issue.3-4, 2010. ,
DOI : 10.1016/j.jbiotec.2010.03.019
Hamster Brown-Adipose-Tissue Mitochondria. The Chloride Permeability of the Inner Membrane under Respiring Conditions, the Influence of Purine Nucleotides, European Journal of Biochemistry, vol.104, issue.3, pp.585-593, 1974. ,
DOI : 10.1016/0005-2728(72)90094-1
Hamster Brown-Adipose-Tissue Mitochondria. Purine Nucleotide Control of the Ion Conductance of the Inner Membrane, the Nature of the Nucleotide Binding Site, European Journal of Biochemistry, vol.25, issue.2, pp.223-228, 1976. ,
DOI : 10.1016/0304-4173(75)90013-0
Brown-Adipose-Tissue Mitochondria. The Influence of Albumin and Nucleotides on Passive Ion Permeabilities, European Journal of Biochemistry, vol.7, issue.3, pp.523-530, 1973. ,
DOI : 10.1016/0014-4827(72)90579-4
Mitochondrial Morphology and Dynamics in Yeast and Multicellular Eukaryotes, Annual Review of Genetics, vol.39, issue.1, pp.503-536, 2005. ,
DOI : 10.1146/annurev.genet.38.072902.093019
Diseases caused by defects of mitochondrial carriers: A review, Biochimica et Biophysica Acta (BBA) - Bioenergetics, vol.1777, issue.7-8, pp.564-578, 2008. ,
DOI : 10.1016/j.bbabio.2008.03.008
Structure and function of mitochondrial carriers - Role of the transmembrane helix P and G residues in the gating and transport mechanism, FEBS Letters, vol.41, issue.9, 2009. ,
DOI : 10.1016/j.febslet.2009.10.063
Fluorinated and hemifluorinated surfactants as alternatives to detergents for membrane protein cell-free synthesis, Biochemical Journal, vol.403, issue.1, pp.183-187, 2007. ,
DOI : 10.1042/BJ20061473
URL : https://hal.archives-ouvertes.fr/hal-00169092
Structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside, Nature, vol.426, issue.6962, pp.39-44, 2003. ,
DOI : 10.1038/nature02056
Nucleotide exchange in mitochondria: insight at a molecular level, Current Opinion in Structural Biology, vol.14, issue.4, pp.420-425, 2004. ,
DOI : 10.1016/j.sbi.2004.06.009
Adenine nucleotide translocation of mitochondria, 1968. ,
Unspecific permeation and specific exchange of adenine nucleotides in liver mitochondria, Biochimica et Biophysica Acta (BBA) - General Subjects, vol.104, issue.1, pp.312-315, 1965. ,
DOI : 10.1016/0304-4165(65)90258-8
Amphipols: polymeric surfactants for membrane biology research, Cell Mol Life Sci, vol.60, pp.1559-1574, 2003. ,
Reprint of: High-Level Expression of Soluble Protein in Escherichia coli Using a His6-Tag and Maltose-Binding-Protein Double-Affinity Fusion System, Protein Expression and Purification, vol.10, pp.309-319, 1997. ,
DOI : 10.1016/j.pep.2011.08.024
Mitochondrial import and the twin-pore translocase, Nature Reviews Molecular Cell Biology, vol.377, issue.7, pp.519-530, 2004. ,
DOI : 10.1016/S0167-4889(02)00266-5
Brown-adipose-tissue mitochondria: the regulation of the 32 000-Mr uncoupling protein by fatty acids and purine nucleotides, European Journal of Biochemistry, vol.75, issue.1-2, pp.197-203, 1983. ,
DOI : 10.1016/0014-5793(80)80614-4
Retinoids activate proton transport by the uncoupling proteins UCP1 and UCP2, The EMBO Journal, vol.18, issue.21, pp.5827-5833, 1999. ,
DOI : 10.1093/emboj/18.21.5827
Alkylsulfonates activate the uncoupling protein UCP1: implications for the transport mechanism, Biochimica et Biophysica Acta (BBA) - Bioenergetics, vol.1608, issue.2-3, pp.122-130, 2004. ,
DOI : 10.1016/j.bbabio.2003.11.001
Purification of the carboxy-atractylate binding protein from mitochondria, FEBS Letters, vol.55, issue.1, pp.133-138, 1975. ,
DOI : 10.1016/0014-5793(75)80127-X
Reconstitution of membrane proteins into liposomes: application to energy-transducing membrane proteins, Biochimica et Biophysica Acta (BBA) - Bioenergetics, vol.1231, issue.3, pp.223-246, 1995. ,
DOI : 10.1016/0005-2728(95)00091-V
Mitochondrial carriers in the cytoplasmic state have a common substrate binding site, Proceedings of the National Academy of Sciences, vol.103, issue.8, pp.2617-2622, 2006. ,
DOI : 10.1073/pnas.0509994103
NMR Structure of Mistic, a Membrane-Integrating Protein for Membrane Protein Expression, Science, vol.307, issue.5713, pp.1317-1321, 2005. ,
DOI : 10.1126/science.1106392
The biology of mitochondrial uncoupling proteins, Diabetes, vol.53, issue.1, pp.130-135, 2004. ,
Production of membrane proteins using cell-free expression systems, PROTEOMICS, vol.21, issue.19, pp.3933-3946, 2008. ,
DOI : 10.1002/pmic.200800171
Membrane proteins, lipids and detergents: not just a soap opera, Biochimica et Biophysica Acta (BBA) - Biomembranes, vol.1666, issue.1-2, pp.105-117, 2004. ,
DOI : 10.1016/j.bbamem.2004.04.011
Within brown-fat cells, UCP1-mediated fatty acid-induced uncoupling is independent of fatty acid metabolism, Biochimica et Biophysica Acta (BBA) - Bioenergetics, vol.1777, issue.7-8, pp.642-650, 2008. ,
DOI : 10.1016/j.bbabio.2008.04.038
Native UCP1 Displays Simple Competitive Kinetics between the Regulators Purine Nucleotides and Fatty Acids, Journal of Biological Chemistry, vol.279, issue.37, pp.38236-38248, 2004. ,
DOI : 10.1074/jbc.M402375200
A phylogenetic analysis of the cytochrome b and cytochrome c oxidase I genes supports an origin of mitochondria from within the Rickettsiaceae1The nucleotide sequences in this paper have been deposited in the EMBL sequence database under accession Nos. Y13854 (cob) and Y13855 (cox1).1, Biochimica et Biophysica Acta (BBA) - Bioenergetics, vol.1365, issue.3, pp.545-551, 1998. ,
DOI : 10.1016/S0005-2728(98)00099-1
Fatty acid circuit as a physiological mechanism of uncoupling of oxidative phosphorylation, FEBS Letters, vol.26, issue.3, pp.158-162, 1991. ,
DOI : 10.1016/0014-5793(91)80658-P
Structural investigation of the C-terminal catalytic fragment of presenilin 1, Proceedings of the National Academy of Sciences, vol.107, issue.21, 2010. ,
DOI : 10.1073/pnas.1000778107
Differential expression of adenine nucleotide translocator isoforms in mammalian tissues and during muscle cell differentiation, J Biol Chem, vol.267, pp.14592-14597, 1992. ,
Uncoupling protein 1 inhibition by purine nucleotides is under the control of the endogenous ubiquinone redox state, Biochemical Journal, vol.277, issue.2, pp.297-306, 2009. ,
DOI : 10.1074/jbc.M402375200
URL : https://hal.archives-ouvertes.fr/hal-00479239
Expression of a Plastidic ATP/ADP Transporter Gene in Escherichia coli Leads to a Functional Adenine Nucleotide Transport System in the Bacterial Cytoplasmic Membrane, Journal of Biological Chemistry, vol.273, issue.16, pp.9630-9636, 1998. ,
DOI : 10.1074/jbc.273.16.9630
Photoaffinity labeling of the uncoupling protein UCP1 with retinoic acid: ubiquinone favors binding, FEBS Letters, vol.284, issue.1-3, pp.63-65, 2002. ,
DOI : 10.1016/S0014-5793(02)03116-2
Substitutional mutations in the uncoupling protein-specific sequences of mitochondrial uncoupling protein UCP1 lead to the reduction of fatty acid-induced H+ uniport, The International Journal of Biochemistry & Cell Biology, vol.35, issue.2, pp.212-220, 2003. ,
DOI : 10.1016/S1357-2725(02)00131-0
Transport Kinetics of Uncoupling Proteins: ANALYSIS OF UCP1 RECONSTITUTED IN PLANAR LIPID BILAYERS, Journal of Biological Chemistry, vol.278, issue.35, pp.32497-32500, 2003. ,
DOI : 10.1074/jbc.M303721200
Cold-activated brown adipose tissue in healthy men, N Engl J Med, vol.360, pp.1500-1508, 2009. ,
Membrane lipids: where they are and how they behave, Nature Reviews Molecular Cell Biology, vol.18, issue.2, pp.112-124, 2008. ,
DOI : 10.1038/nrm2330
Evolutionary Relationships among Eubacterial Groups as Inferred from GroEL (Chaperonin) Sequence Comparisons, International Journal of Systematic Bacteriology, vol.44, issue.3, pp.527-533, 1994. ,
DOI : 10.1099/00207713-44-3-527
Action of potassium atractylate on oxidative phosphorylation in mitochondria and in submitochondrial particles, Biochimica et Biophysica Acta, vol.60, issue.2, pp.284-300, 1962. ,
DOI : 10.1016/0006-3002(62)90404-3
Molecular aspects of sutrcture-function relationships in mitochondrial adnine nucleotide carrier, Structure and Proprieties of Cell Mambranes, vol.2, pp.139-179, 1985. ,
Functional brown adipose tissue in healthy adults, N Engl J Med, vol.360, pp.1518-1525, 2009. ,
Identification of the Mitochondrial GTP/GDP Transporter in Saccharomyces cerevisiae, Journal of Biological Chemistry, vol.279, issue.20, pp.20850-20857, 2004. ,
DOI : 10.1074/jbc.M313610200
Tuning Escherichia coli for membrane protein overexpression, Proc Natl Acad Sci, vol.105, pp.14371-14376, 2008. ,
Effect of fatty acids on H+ transport activity of the reconstituted uncoupling protein, J Biol Chem, vol.269, pp.2508-2515, 1994. ,
High yield cell-free production of integral membrane proteins without refolding or detergents, Biochimica et Biophysica Acta (BBA) - Biomembranes, vol.1778, issue.5, pp.1237-1250, 2008. ,
DOI : 10.1016/j.bbamem.2008.01.023
Mitochondrial origins., Proceedings of the National Academy of Sciences, vol.82, issue.13, pp.4443-4447, 1985. ,
DOI : 10.1073/pnas.82.13.4443
Adenine nucleotide translocase: a component of the phylogenetically conserved cell death machinery Publications et communications orales Publications Nury H, Blesneac I, Ravaud S and Pebay-Peyroula E, Structural approaches of the mitochondrial carrier family, Cell Death Differ Methods in Molecular Biology : Membrane Protein Structure Determination Ed. J.J. Lacapère. Accepté, vol.16, pp.1419-1425, 2009. ,
Crystallization of the membrane protein hVDAC1 produced in cell-free system, Biochimica et Biophysica Acta (BBA) - Biomembranes, vol.1798, issue.8, 2010. ,
DOI : 10.1016/j.bbamem.2010.04.010
URL : https://hal.archives-ouvertes.fr/hal-00821157
A Simple Method for the Reconstitution of Membrane Proteins into Giant Unilamellar Vesicles, Journal of Membrane Biology, vol.7, issue.1-3, pp.1-385, 2010. ,
DOI : 10.1007/s00232-010-9227-8
URL : https://hal.archives-ouvertes.fr/hal-00821162
Single-step production of functional OEP24 proteoliposomes, Protein Expression and Purification, vol.69, issue.1, pp.106-117, 2010. ,
DOI : 10.1016/j.pep.2009.07.004
URL : https://hal.archives-ouvertes.fr/hal-00821165
Membrane Protein Production, Crystallization and Crystallography, 2009. ,
GDR 2478 meeting « Membrane proteins : Molecular Proprieties in amphiphilic environment, 2009. ,
GDR 2478 meeting « Membrane proteins : Molecular Proprieties in amphiphilic environment, 2008. ,
CNRS workshop « Heterologous expression of integral membrane proteins, 2008. ,