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Électrodes nanocomposites pour applications en microfluidique

Mathieu Brun 1 
1 INL - LOCI - INL - Lab-On-Chip et Instrumentation
INL - Institut des Nanotechnologies de Lyon
Abstract : The work presented in this thesis deals with the integration of non-conventional materials in microfluidic systems. It aims to demonstrate the potential of cPDMS, a conductive nanocomposite material made up of polydimethylsiloxane matrix mixed with carbon nanoparticles. Compatible with the usual technological processes such as soft lithography, cPDMS can be microstructured in a large range of thicknesses and geometries. Moreover, cPDMS can be quickly, irreversibly and perfectly sealed to glass, PDMS and silicon substrates, something that is not possible for conventional metallic electrodes. The first part of the manuscript is centered on the characterization of this material. Its electrical and surface properties that may turn out critical for microfluidic applications have been particularly studied. Electric fields present many opportunities to perform key functions in microfluidic (detection, separation, fluid or particles handling). We have chosen to assess the potential of cPDMS electrodes for two kinds of applications. Aspects of detection were first demonstrated using cyclic voltammetry measurements. This electrochemical method has enabled both to characterize the cPDMS surface while validating its potential as an electrochemical analysis tool. In the last part of this manuscript, cPDMS was tested for the electrokinetic manipulation of particles through thre study of different electrical fields with induced phenomena. This has led to the development of microfluidic devices (integrating cPDMS electrodes) designed for cell lysis and cells electrofusion.
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Submitted on : Tuesday, October 23, 2012 - 2:42:12 PM
Last modification on : Saturday, September 24, 2022 - 2:58:04 PM
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  • HAL Id : tel-00744588, version 1


Mathieu Brun. Électrodes nanocomposites pour applications en microfluidique. Autre [cond-mat.other]. Université Claude Bernard - Lyon I, 2011. Français. ⟨NNT : 2011LYO10332⟩. ⟨tel-00744588⟩



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