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Crystal-chemistry and reactivity of fibrous amphiboles of environmental and health interest

Abstract : This work concerns the physico-chemical and structural characterisation of mineral fibres (asbestos) and the comprehension of the chemical and molecular mechanisms which are responsible of the development of human pathologies specific to their inhalation. In particular, in this work we performed a crystallochemical and surface reactivity study of floro-edenite, a natural amphibole of volcanic origin recently discovered in Biancavilla (Sicily, Italy). The properties of this mineral were compared to those of other natural mineral fibres, such as tremolite and chrysotile, also present in ophiolitic formations of the Italian peninsula. This work consists of several different parts, which are proof of its multidisciplinary and applied character. In the first part, we studied the mineralogical, chemical and morphological analysis of previously purified natural fibres of fluoro-edenite. The main goal of this part was to determine precisely the crystallographic structure and the composition of this material. This information has been of fundamental importance in the second part of this study, which concerned the toxicochemical properties and the surface reactivity of this mineral. In order to underline the possible pathogenic effect of the inhalation of these fibres, these properties were compared to those of other mineral fibres, such as tremolite and chrysotile, the toxicological properties of which are already known.The second part of this study was finally validated by parallel in vitro and in vivo tests of these materials, in collaboration with a biomedical research group.
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  • HAL Id : tel-00814192, version 1


Alessandro Pacella. Crystal-chemistry and reactivity of fibrous amphiboles of environmental and health interest. Material chemistry. Université Pierre et Marie Curie - Paris VI; Università di Roma "La Sapienza", 2009. English. ⟨NNT : 2009PA066208⟩. ⟨tel-00814192⟩



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