S. S. Bates, D. J. Douglas, G. J. Doucette, and C. Léger, Enhancement of domoic acid production by reintroducing bacteria to axenic cultures of the diatomPseudo-nitzschia multiseries, Natural Toxins, vol.56, issue.6, pp.428-435, 1995.
DOI : 10.1002/nt.2620030605

S. S. Bates, J. Gaudet, I. Kaczmarska, and J. M. Ehrman, Interaction between bacteria and the domoic-acid-producing diatom Pseudo-nitzschia multiseries (Hasle) Hasle; can bacteria produce domoic acid autonomously?, Harmful Algae, vol.3, issue.1, pp.11-20, 2004.
DOI : 10.1016/j.hal.2003.08.001

C. P. Brussaard and R. Riegman, Influence of bacteria on phytoplankton cell mortality with phosphorus or nitrogen as the algal-growth-limiting nutrient, Aquatic Microbial Ecology, vol.14, issue.3, pp.271-280, 1998.
DOI : 10.3354/ame014271

J. P. Descy, B. Leporcq, L. Viroux, C. Francois, and P. Servais, Phytoplankton production, exudation and bacterial reassimilation in the River Meuse (Belgium), Journal of Plankton Research, vol.24, issue.3, pp.161-166, 2002.
DOI : 10.1093/plankt/24.3.161

D. J. Douglas, S. S. Bates, L. A. Bourque, and R. C. Selvin, Domoic acid production by axenic and non-axenic cultures of the pennate diatom Nitzschia pungens f. multiseries Toxic Phytoplankton Blooms in the Sea, pp.595-600, 1993.

A. L. Annett, S. Lapi, T. J. Ruth, and M. T. Maldonado, The effects of Cu and Fe availability on the growth and Cu:C ratios of marine diatoms, Limnology and Oceanography, vol.53, issue.6, pp.2451-2461, 2008.
DOI : 10.4319/lo.2008.53.6.2451

S. S. Bates, D. J. Douglas, G. J. Doucette, and C. Léger, Enhancement of domoic acid production by reintroducing bacteria to axenic cultures of the diatomPseudo-nitzschia multiseries, Natural Toxins, vol.56, issue.6, pp.428-435, 1995.
DOI : 10.1002/nt.2620030605

S. S. Bates, C. Léger, M. F. Satchwell, G. L. Boyer, G. M. Hallegraeff et al., The effects of iron on domoic acid production by Pseudo-nitzschia multiseries, Harmful Algal Blooms Intergovernmental Oceanographic Commission of UNESCO, pp.320-323, 2000.

P. W. Boyd, E. , and M. J. , The biogeochemical cycle of iron in the ocean, Nature Geoscience, vol.31, issue.10, pp.675-682, 2010.
DOI : 10.1038/ngeo964

E. Bucciarelli, P. Pondaven, and G. Sarthou, Effects of an iron-light co-limitation on the elemental composition (Si, C, N) of the marine diatoms <I>Thalassiosira oceanica</I> and <I>Ditylum brightwellii</I>, Biogeosciences, vol.7, issue.2, pp.657-669, 2010.
DOI : 10.5194/bg-7-657-2010-supplement

A. P. Carvalho, I. Pontes, H. Gaspar, and F. X. Malcata, Metabolic relationships between macro- and micronutrients, and the eicosapentaenoic acid and docosahexaenoic acid contents of Pavlova lutheri, Enzyme and Microbial Technology, vol.38, issue.3-4, pp.358-366, 2006.
DOI : 10.1016/j.enzmictec.2005.05.014

K. H. Coale, Effects of iron, manganese, copper, and zinc enrichments on productivity and biomass in the subarctic Pacific, Limnology and Oceanography, vol.36, issue.8, pp.1851-1864, 1991.
DOI : 10.4319/lo.1991.36.8.1851

K. H. Coale, K. S. Johnson, F. P. Chavez, K. O. Buesseler, R. T. Barber et al., Southern Ocean Iron Enrichment Experiment: Carbon Cycling in High- and Low-Si Waters, Science, vol.304, issue.5669, pp.408-414, 2004.
DOI : 10.1126/science.1089778

H. J. De-baar, P. W. Boyd, K. H. Coale, M. R. Landry, A. Tsuda et al., Synthesis of iron fertilization experiments: From the Iron Age in the Age of Enlightenment, Journal of Geophysical Research, vol.101, issue.47, pp.9-16, 2005.
DOI : 10.1029/2004JC002601

D. J. Douglas, S. S. Bates, L. A. Bourque, and R. C. Selvin, Domoic acid production by axenic and non-axenic cultures of the pennate diatom Nitzschia pungens f. multiseries, Toxic Phytoplankton Blooms in the Sea, pp.595-600, 1993.

P. G. Falkowski, R. , and J. A. , Aquatic photosynthesis, In. Scientific, B, 1997.
DOI : 10.1515/9781400849727

J. Fehling, K. Davidson, and S. S. Bates, Growth dynamics of non-toxic Pseudo-nitzschia delicatissima and toxic P. seriata (Bacillariophyceae) under simulated spring and summer photoperiods, Harmful Algae, vol.4, issue.4, pp.763-769, 2005.
DOI : 10.1016/j.hal.2004.11.002

M. Giordano, M. Kansiz, P. Heraud, J. Beardall, B. Wood et al., FOURIER TRANSFORM INFRARED SPECTROSCOPY AS A NOVEL TOOL TO INVESTIGATE CHANGES IN INTRACELLULAR MACROMOLECULAR POOLS IN THE MARINE MICROALGA CHAETOCEROS MUELLERII (BACILLARIOPHYCEAE), Journal of Phycology, vol.37, issue.2, pp.271-279, 2001.
DOI : 10.1046/j.1529-8817.2001.037002271.x

R. M. Greene, R. J. Geider, Z. Kolber, and P. G. Falkowski, Iron-Induced Changes in Light Harvesting and Photochemical Energy Conversion Processes in Eukaryotic Marine Algae, PLANT PHYSIOLOGY, vol.100, issue.2, pp.565-575, 1992.
DOI : 10.1104/pp.100.2.565

T. Y. Ho, A. Quigg, Z. V. Finkel, A. J. Milligan, K. Wyman et al., THE ELEMENTAL COMPOSITION OF SOME MARINE PHYTOPLANKTON1, Journal of Phycology, vol.39, issue.6, pp.1145-1159, 2003.
DOI : 10.1111/j.0022-3646.2003.03-090.x

K. A. Hubbard, G. Rocap, and E. V. Armbrust, (BACILLARIOPHYCEAE), Journal of Phycology, vol.37, issue.3, pp.637-649, 2008.
DOI : 10.1111/j.1529-8817.2008.00518.x

R. J. Hudson and F. M. Morel, lron transport in marine phytoplankton: Kinetics of cellular and medium coordination reactions, Limnology and Oceanography, vol.35, issue.5, pp.1002-1020, 1990.
DOI : 10.4319/lo.1990.35.5.1002

L. A. Inda, D. L. Erdner, M. L. Peleato, A. , and D. M. , Cytochrome c6 isolated from the marine diatom Thalassiosira weissflogii, Phytochemistry, vol.51, issue.1, pp.1-4, 1999.
DOI : 10.1016/S0031-9422(98)00493-2

I. Kaczmarska, J. M. Ehrman, S. S. Bates, D. H. Green, C. Léger et al., Diversity and distribution of epibiotic bacteria on Pseudo-nitzschia multiseries (Bacillariophyceae) in culture, and comparison with those on diatoms in native seawater, Harmful Algae, vol.4, issue.4, pp.725-741, 2005.
DOI : 10.1016/j.hal.2004.10.001

M. D. Keller, W. K. Bellows, and R. R. Guillard, Microwave treatment for sterilization of phytoplankton culture media, Journal of Experimental Marine Biology and Ecology, vol.117, issue.3, pp.279-283, 1988.
DOI : 10.1016/0022-0981(88)90063-9

L. Fontaine, S. Quinn, J. M. Nakamoto, S. S. Page, M. D. Gohre et al., Copper-Dependent Iron Assimilation Pathway in the Model Photosynthetic Eukaryote Chlamydomonas reinhardtii, Eukaryotic Cell, vol.1, issue.5, pp.736-757, 2002.
DOI : 10.1128/EC.1.5.736-757.2002

L. Roche, J. Geider, R. J. Graziano, L. M. Murray, H. et al., INDUCTION OF SPECIFIC PROTEINS IN EUKARYOTIC ALGAE GROWN UNDER IRON-, PHOSPHORUS-, OR NITROGEN-DEFICIENT CONDITIONS1, Journal of Phycology, vol.29, issue.6, pp.767-777, 1993.
DOI : 10.1111/j.0022-3646.1993.00767.x

M. Osada and J. E. Stewart, Gluconic acid/gluconolactone: physiological influences on domoic acid production by bacteria associated with Pseudo-nitzschia multiseries, Aquatic Microbial Ecology, vol.12, 1997.
DOI : 10.3354/ame012203

Y. Pan, S. S. Bates, and A. D. Cembella, Environmental stress and domoic acid production byPseudo-nitzschia: a physiological perspective, Natural Toxins, vol.33, issue.3-4, pp.127-135, 1998.
DOI : 10.1002/(SICI)1522-7189(199805/08)6:3/4<127::AID-NT9>3.0.CO;2-2

G. Peers, P. , and N. M. , A role for manganese in superoxide dismutases and growth of iron-deficient diatoms, Limnology and Oceanography, vol.49, issue.5, pp.1774-1783, 2004.
DOI : 10.4319/lo.2004.49.5.1774

G. Peers, P. , and N. M. , Copper-containing plastocyanin used for electron transport by an oceanic diatom, Nature, vol.49, issue.7091, pp.341-344, 2006.
DOI : 10.1021/es001213r

G. Peers, S. A. Quesnel, P. , and N. M. , Copper requirements for iron acquisition and growth of coastal and oceanic diatoms, Limnology and Oceanography, vol.50, issue.4, pp.1149-1158, 2005.
DOI : 10.4319/lo.2005.50.4.1149

D. Petroutsos, A. M. Terauchi, A. Busch, I. Hirschmann, S. S. Merchant et al., PGRL1 Participates in Iron-induced Remodeling of the Photosynthetic Apparatus and in Energy Metabolism in Chlamydomonas reinhardtii, Journal of Biological Chemistry, vol.284, issue.47, pp.32770-32781, 2009.
DOI : 10.1074/jbc.M109.050468

N. M. Price, G. I. Harrison, J. G. Hering, R. J. Hudson, P. M. Nirel et al., Preparation and chemistry of the artificial algal culture medium Aquil, Biol. Oceanogr, vol.6, pp.443-461, 1988.

J. A. Raven, M. C. Evans, and R. E. Korb, The role of trace metals in photosynthetic electron transport in O2-evolving organisms, Photosynthesis Research, vol.60, issue.2/3, pp.111-149, 1999.
DOI : 10.1023/A:1006282714942

E. Rue and K. Bruland, Domoic acid binds iron and copper: a possible role for the toxin produced by the marine diatom Pseudo-nitzschia, Marine Chemistry, vol.76, issue.1-2, pp.127-134, 2001.
DOI : 10.1016/S0304-4203(01)00053-6

G. Sarthou, K. R. Timmermans, S. Blain, and P. Treguer, Growth physiology and fate of diatoms in the ocean: a review, Journal of Sea Research, vol.53, issue.1-2, pp.25-42, 2005.
DOI : 10.1016/j.seares.2004.01.007

URL : https://hal.archives-ouvertes.fr/hal-00456424

M. W. Silver, S. Bargu, S. L. Coale, C. R. Benitez-nelson, A. C. Garcia et al., Toxic diatoms and domoic acid in natural and iron enriched waters of the oceanic Pacific, Proceedings of the National Academy of Sciences, vol.107, issue.48, pp.20762-20767, 2010.
DOI : 10.1073/pnas.1006968107

J. E. Stewart, Bacterial involvement in determining domoic acid levels in Pseudo-nitzschia multiseries cultures, Aquatic Microbial Ecology, vol.50, pp.135-144, 2008.
DOI : 10.3354/ame01159

J. E. Stewart, L. J. Marks, C. R. Wood, S. M. Risser, and S. Gray, Symbiotic relations between bacteria and the domoic acid producing diatom Pseudo-nitzschia multiseries and the capacity of these bacteria for gluconic acid/gluconolactone formation, Aquatic Microbial Ecology, vol.12, pp.211-221, 1997.
DOI : 10.3354/ame012211

R. F. Strzepek, H. , and P. J. , Photosynthetic architecture differs in coastal and oceanic diatoms, Nature, vol.25, issue.7009, pp.689-692, 2004.
DOI : 10.1016/0005-2728(82)90320-6

W. G. Sunda, ) Trace metal interactions with marine phytoplankton, Biological Oceanography, vol.6, pp.411-442, 1988.

W. G. Sunda and S. A. Huntsman, Iron uptake and growth limitation in oceanic and coastal phytoplankton, Marine Chemistry, vol.50, issue.1-4, pp.189-206, 1995.
DOI : 10.1016/0304-4203(95)00035-P

W. G. Sunda, D. G. Swift, and S. A. Huntsman, Low iron requirement for growth in oceanic phytoplankton, Nature, vol.351, issue.6321, pp.55-57, 1991.
DOI : 10.1038/351055a0

W. G. Sunda, N. M. Price, F. M. Morel, and R. A. Andersen, Trace Metal Ion Buffers and Their Use in Culture Studies, Algal culturing techniques, pp.35-63, 2005.
DOI : 10.1016/B978-012088426-1/50005-6

A. E. Thessen, Q. Dortch, M. L. Parsons, and W. Morrison, SPECIES (BACILLARIOPHYCEAE) GROWTH AND DISTRIBUTION, Journal of Phycology, vol.41, issue.1, pp.21-29, 2005.
DOI : 10.1111/j.1529-8817.2005.04077.x

V. L. Trainer, M. L. Wells, W. P. Cochlan, C. G. Trick, B. D. Bill et al., An ecological study of a massive bloom of toxigenic Pseudo-nitzschia cuspidata off the Washington State coast, Limnology and Oceanography, vol.54, issue.5, pp.1461-1474, 2009.
DOI : 10.4319/lo.2009.54.5.1461

C. G. Trick, B. D. Bill, W. P. Cochlan, M. L. Wells, V. L. Trainer et al., Iron enrichment stimulates toxic diatom production in high-nitrate, low-chlorophyll areas, Proceedings of the National Academy of Sciences, vol.107, issue.13, 2010.
DOI : 10.1073/pnas.0910579107

A. Ventrella, L. Catucci, G. Mascolo, A. Corcelli, and A. Agostiano, Isolation and characterization of lipids strictly associated to PSII complexes: Focus on cardiolipin structural and functional role, Biochimica et Biophysica Acta (BBA) - Biomembranes, vol.1768, issue.6, pp.1620-1627, 2007.
DOI : 10.1016/j.bbamem.2007.03.024

M. L. Wells, C. G. Trick, W. P. Cochlan, M. P. Hughes, and V. L. Trainer, Domoic acid: The synergy of iron, copper, and the toxicity of diatoms, Limnology and Oceanography, vol.50, issue.6, pp.1908-1917, 2005.
DOI : 10.4319/lo.2005.50.6.1908

S. H. Zhu, J. A. Guo, M. T. Maldonado, and B. R. Green, EFFECTS OF IRON AND COPPER DEFICIENCY ON THE EXPRESSION OF MEMBERS OF THE LIGHT-HARVESTING FAMILY IN THE DIATOM THALASSIOSIRA PSEUDONANA (BACILLARIOPHYCEAE)1, Journal of Phycology, vol.1797, issue.5, pp.974-981, 2010.
DOI : 10.1111/j.1529-8817.2010.00884.x

N. G. Adams, M. Lesoing, and V. L. Trainer, Environmental conditions associated with domoic acid in razor clams on the Washington coast, Journal of Shellfish Research, vol.19, pp.1007-1015, 2000.

A. L. Annett, S. Lapi, T. J. Ruth, and M. T. Maldonado, The effects of Cu and Fe availability on the growth and Cu:C ratios of marine diatoms, Limnology and Oceanography, vol.53, issue.6, pp.2451-2461, 2008.
DOI : 10.4319/lo.2008.53.6.2451

K. J. Appenroth, J. Stöckel, A. Srivastava, and R. J. Strasser, Multiple effects of chromate on the photosynthetic apparatus of Spirodela polyrhiza as probed by OJIP chlorophyll a fluorescence measurements, Environmental Pollution, vol.115, issue.1, pp.49-64, 2001.
DOI : 10.1016/S0269-7491(01)00091-4

S. C. Apte and G. M. Day, Dissolved metal concentrations in the Torres strait and Gulf of Papua, Marine Pollution Bulletin, vol.36, issue.4, pp.298-304, 1998.
DOI : 10.1016/S0025-326X(98)00188-X

S. Bargu, B. Marinovic, S. Mansergh, and M. W. Silver, Feeding responses of krill to the toxin-producing diatom Pseudo-nitzschia, Journal of Experimental Marine Biology and Ecology, vol.284, issue.1-2, pp.87-104, 2003.
DOI : 10.1016/S0022-0981(02)00494-X

S. S. Bates, Ecophysiology and metabolism of ASP toxin production In: Physiological ecology of harmful algal blooms, 1998.

S. S. Bates, C. J. Bird, A. S. De-freitas, R. Foxall, M. Gilgan et al., Pennate diatom Nitzschia pungens as the primary source of domoic acid, shellfish from eastern Prince Edward, 1989.

S. S. Bates, D. J. Douglas, G. J. Doucette, and C. Léger, Enhancement of domoic acid production by reintroducing bacteria to axenic cultures of the diatomPseudo-nitzschia multiseries, Natural Toxins, vol.56, issue.6, pp.428-435, 1995.
DOI : 10.1002/nt.2620030605

S. S. Bates, J. Gaudet, I. Kaczmarska, and J. M. Ehrman, Interaction between bacteria and the domoic acid producing diatom Pseudo-nitzschia multiseries (Hasle) Hasle; can bacteria produce domoic acid autonomously? Harmful Algae, pp.11-20, 2004.

S. S. Bates, C. Léger, M. F. Satchwell, and G. L. Boyer, The effects of iron on domoic acid production by Pseudo-nitzschia multiseries, Harmful Algal Blooms Intergovernmental Oceanographic Commission of UNESCO, pp.320-323, 2000.

P. W. Boyd and M. J. Ellwood, The biogeochemical cycle of iron in the ocean, Nature Geoscience, vol.31, issue.10, pp.675-682, 2010.
DOI : 10.1038/ngeo964

C. P. Brussaard and R. Riegman, Influence of bacteria on phytoplankton cell mortality with phosphorus or nitrogen as the algal-growth-limiting nutrient, Aquatic Microbial Ecology, vol.14, pp.271-280, 1998.
DOI : 10.3354/ame014271

K. H. Coale, K. S. Johnson, F. P. Chavez, K. O. Buesseler, R. T. Barber et al., Southern Ocean Iron Enrichment Experiment: Carbon Cycling in High- and Low-Si Waters, Science, vol.304, issue.5669, pp.408-414, 2004.
DOI : 10.1126/science.1089778

H. J. De-baar, P. W. Boyd, K. H. Coale, M. R. Landry, A. Tsuda et al., Synthesis of iron fertilization experiments: From the Iron Age in the Age of Enlightenment, Journal of Geophysical Research, vol.101, issue.47, pp.9-16, 2005.
DOI : 10.1029/2004JC002601

D. J. Douglas, S. S. Bates, L. A. Bourque, and R. C. Selvin, Domoic acid production by axenic and non-axenic cultures of the pennate diatom Nitzschia pungens f. multiseries. In: Toxic Phytoplankton Blooms in the Sea, pp.595-600, 1993.

P. Falkowski, R. J. Scholes, E. Boyle, J. Canadell, D. Canfield et al., The Global Carbon Cycle: A Test of Our Knowledge of Earth as a System, Science, vol.290, issue.5490, pp.291-296, 2000.
DOI : 10.1126/science.290.5490.291

J. Fehling, K. Davidson, and S. S. Bates, Growth dynamics of non-toxic Pseudo-nitzschia delicatissima and toxic P. seriata (Bacillariophyceae) under simulated spring and summer photoperiods, Harmful Algae, vol.4, issue.4, pp.763-769, 2005.
DOI : 10.1016/j.hal.2004.11.002

J. Fehling, K. Davidson, C. J. Bolch, and S. S. Bates, GROWTH AND DOMOIC ACID PRODUCTION BY PSEUDO-NITZSCHIA SERIATA (BACILLARIOPHYCEAE) UNDER PHOSPHATE AND SILICATE LIMITATION1, Journal of Phycology, vol.67, issue.454, pp.674-683, 2004.
DOI : 10.1111/j.1529-8817.2004.03213.x

E. Fouilland and B. Mostajir, Revisited phytoplanktonic carbon dependency of heterotrophic bacteria in freshwaters, transitional, coastal and oceanic waters, FEMS Microbiology Ecology, vol.73, issue.3, pp.419-429, 2010.
DOI : 10.1111/j.1574-6941.2010.00896.x

D. L. Garrison, S. M. Conrad, P. P. Eilers, and E. M. Waldron, CONFIRMATION OF DOMOIC ACID PRODUCTION BY PSEUDONITZSCHIA AUSTRALIS (BACILLARIOPHYCEAE) CULTURES1, Journal of Phycology, vol.28, issue.5, pp.604-607, 1992.
DOI : 10.1111/j.0022-3646.1992.00604.x

M. Giordano, M. Kansiz, P. Heraud, J. Beardall, B. Wood et al., FOURIER TRANSFORM INFRARED SPECTROSCOPY AS A NOVEL TOOL TO INVESTIGATE CHANGES IN INTRACELLULAR MACROMOLECULAR POOLS IN THE MARINE MICROALGA CHAETOCEROS MUELLERII (BACILLARIOPHYCEAE), Journal of Phycology, vol.37, issue.2, pp.271-279, 2001.
DOI : 10.1046/j.1529-8817.2001.037002271.x

F. J. Jochem, Probing the physiological state of phytoplankton at the single-cell level, Scientia Marina, vol.64, issue.2, pp.183-195, 2000.
DOI : 10.3989/scimar.2000.64n2183

T. O. Jones, J. N. Whyte, L. D. Townsend, N. G. Ginther, and G. K. Iwama, Effects of domoic acid on haemolymph pH, PCO2 and PO2 in the Pacific oyster, Crassostrea gigas and the California mussel, Mytilus californianus, Aquatic Toxicology, vol.31, issue.1, pp.43-55, 1995.
DOI : 10.1016/0166-445X(94)00057-W

I. Kaczmarska, J. M. Ehrman, S. S. Bates, D. H. Green, C. Léger et al., Diversity and distribution of epibiotic bacteria on Pseudo-nitzschia multiseries (Bacillariophyceae) in culture, and comparison with those on diatoms in native seawater, Harmful Algae, vol.4, issue.4, pp.725-741, 2005.
DOI : 10.1016/j.hal.2004.10.001

A. Lelong, H. Hégaret, and P. Soudant, Cell-based measurements to assess physiological status of Pseudo-nitzschia multiseries, a toxic diatom, Research in Microbiology, vol.162, issue.9, pp.969-981, 2011.
DOI : 10.1016/j.resmic.2011.06.005

URL : https://hal.archives-ouvertes.fr/hal-00648976

A. Lelong, D. F. Jolley, P. Soudant, and H. Hégaret, The effects of copper toxicity on Pseudo-nitzschia spp. physiology and domoic acid production. Aquatic Toxicology, pp.118-11937, 2012.

A. Lelong, H. Hégaret, P. Soudant, and S. S. Bates, Pseudo-nitzschia (Bacillariophyceae) species, domoic acid and amnesic shellfish poisoning: revisiting previous paradigms, Phycologia, vol.51, issue.2, pp.168-216, 2012.
DOI : 10.2216/11-37.1

A. Lelong, H. Hégaret, and P. Soudant, in prep.-a. How does Pseudo-nitzschia multiseries, a toxic diatom, compete with a diatom of the Chaetoceros genus?, Applied and Environmental Microbiology

A. Lelong, H. Hégaret, and P. Soudant, in prep-b. Modification of domoic acid production and cell physiology after exchange of bacterial community between toxic Pseudo-nitzschia multiseries and non toxic Pseudo-nitzschia delicatissima, Harmful Algae

J. L. Levy, J. L. Stauber, and D. F. Jolley, Sensitivity of marine microalgae to copper: The effect of biotic factors on copper adsorption and toxicity. Science of The Total Environment, pp.141-154, 2007.

N. Lundholm, P. J. Hansen, and Y. Kotaki, Lack of allelopathic effects of the domoic acid-producing marine diatom Pseudo-nitzschia multiseries, Marine Ecology Progress Series, vol.288, pp.21-33, 2005.
DOI : 10.3354/meps288021

M. T. Maldonado, A. E. Allen, J. S. Chong, K. Lin, D. Leus et al., Copper-dependent iron transport in coastal and oceanic diatoms, Limnology and Oceanography, vol.51, issue.4, pp.1729-1743, 2006.
DOI : 10.4319/lo.2006.51.4.1729

A. Marchetti, N. D. Sherry, H. Kiyosawa, A. Tsuda, and P. J. Harrison, Phytoplankton processes during a mesoscale iron enrichment in the NE subarctic Pacific: Part I - Biomass and assemblage. Deep-Sea Research. Part II, pp.2095-2113, 2006.

A. Mcminn, H. Hattori, T. Hirawake, and A. Iwamoto, Preliminary investigation of Okhotsk Sea ice algae; taxonomic composition and photosynthetic activity, Polar Biology, vol.42, issue.8, pp.1011-1015, 2008.
DOI : 10.1007/s00300-008-0433-0

F. M. Morel and N. M. Price, The Biogeochemical Cycles of Trace Metals in the Oceans, Science, vol.300, issue.5621, pp.944-947, 2003.
DOI : 10.1126/science.1083545

E. Nézan, N. Chomérat, G. Bilien, S. Boulben, A. Duval et al., Pseudonitzschia australis on French Atlantic coast -an unusual toxic bloom, Harmful Algae News N°41, pp.1-2, 2010.

M. Osada and J. E. Stewart, Gluconic acid/gluconolactone: physiological influences on domoic acid production by bacteria associated with Pseudo-nitzschia multiseries, Aquatic Microbial Ecology, vol.12, pp.203-209, 1997.
DOI : 10.3354/ame012203

Y. L. Pan, M. L. Parsons, M. Busman, P. D. Moeller, Q. Dortch et al., Pseudo-nitzschia sp. cf. pseudodelicatissima - a confirmed producer of domoic acid from the northern Gulf of Mexico, Marine Ecology Progress Series, vol.220, pp.83-92, 2001.
DOI : 10.3354/meps220083

G. Peers, S. A. Quesnel, and N. M. Price, Copper requirements for iron acquisition and growth of coastal and oceanic diatoms, Limnology and Oceanography, vol.50, issue.4, pp.1149-1158, 2005.
DOI : 10.4319/lo.2005.50.4.1149

O. M. Pulido, Domoic Acid Toxicologic Pathology: A Review, Marine Drugs, vol.6, issue.2, pp.180-219, 2008.
DOI : 10.3390/md6020180

S. Quijano-scheggia, E. Garcés, E. Flo, M. Fernandez-tejedor, J. Diogène et al., Bloom dynamics of the genus Pseudo-nitzschia (Bacillariophyceae) in two coastal bays (NW Mediterranean Sea) Scientia Marina, pp.577-590, 2008.

L. Rhodes, P. A. Holland, A. Selwood, and P. Mcnabb, Mass culture of Pseudonitzschia australis for production of a new isomer of domoic acid, 2004.

H. Landsberg, C. R. Tomas, and G. A. Vargo, Harmful Algae, Florida Fish and Wildlife Conservation Commission, Florida Institute of Oceanography, and Intergovernmental Oceanographic Commission of UNESCO, pp.125-127, 2002.

E. Rue and K. Bruland, Domoic acid binds iron and copper: a possible role for the toxin produced by the marine diatom Pseudo-nitzschia, Marine Chemistry, vol.76, issue.1-2, pp.127-134, 2001.
DOI : 10.1016/S0304-4203(01)00053-6

J. G. Rueter, S. W. Chisholm, and F. M. Morel, EFFECTS OF COPPER TOXICITY ON SILICIC ACID UPTAKE AND GROWTH IN THALASSIOSIRA PSEUDONANA1, Journal of Phycology, vol.19, issue.3, pp.270-278, 1981.
DOI : 10.1111/j.1529-8817.1977.tb02892.x

J. Santos-echeandia, L. M. Laglera, R. Prego, and C. M. Van-den-berg, Copper speciation in continental inputs to the Vigo Ria: Sewage discharges versus river fluxes, Marine Pollution Bulletin, vol.56, issue.2, pp.308-317, 2008.
DOI : 10.1016/j.marpolbul.2007.10.021

M. Sapp, A. Wichels, and G. Gerdts, Impacts of Cultivation of Marine Diatoms on the Associated Bacterial Community, Applied and Environmental Microbiology, vol.73, issue.9, pp.3117-3120, 2007.
DOI : 10.1128/AEM.02274-06

C. A. Scholin, F. Gulland, G. J. Doucette, S. Benson, M. Busman et al., Mortality of sea lions along the central California coast linked to a toxic diatom bloom, Nature, vol.39, issue.6765, pp.80-84, 2000.
DOI : 10.1038/47481

H. Shen, Y. Niu, P. Xie, M. Tao, and X. Yang, Morphological and physiological changes in Microcystis aeruginosa as a result of interactions with heterotrophic bacteria, Freshwater Biology, vol.266, issue.6, pp.1065-1080, 2011.
DOI : 10.1111/j.1365-2427.2010.02551.x

T. J. Smayda, Harmful algal blooms: Their ecophysiology and general relevance to phytoplankton blooms in the sea, Limnology and Oceanography, vol.42, issue.5part2, pp.1137-1153, 1997.
DOI : 10.4319/lo.1997.42.5_part_2.1137

T. J. Smayda, Turbulence, watermass stratification and harmful algal blooms: an alternative view and frontal zones as ???pelagic seed banks???, Harmful Algae, vol.1, issue.1, pp.95-112, 2002.
DOI : 10.1016/S1568-9883(02)00010-0

A. Sournia, M. J. Chretiennot-dinet, and M. Ricard, Marine phytoplankton: how many species in the world ocean?, Journal of Plankton Research, vol.13, issue.5, pp.1093-1099, 1991.
DOI : 10.1093/plankt/13.5.1093

M. D. Stephenson and G. H. Leonard, Evidence for the decline of silver and lead and the increase of copper from 1977 to 1990 in the coastal marine waters of California, Marine Pollution Bulletin, vol.28, issue.3, pp.148-153, 1994.
DOI : 10.1016/0025-326X(94)90390-5

J. E. Stewart, Bacterial involvement in determining domoic acid levels in Pseudo-nitzschia multiseries cultures, Aquatic Microbial Ecology, vol.50, pp.135-144, 2008.
DOI : 10.3354/ame01159

J. E. Stewart, L. J. Marks, M. W. Gilgan, E. Pfeiffer, and B. M. Zwicker, Microbial utilization of the neurotoxin domoic acid: blue mussels (<i>Mytilus edulis</i>) and soft shell clams (<i>Mya arenaria</i>) as sources of the microorganisms, Canadian Journal of Microbiology, vol.44, issue.5, pp.456-464, 1998.
DOI : 10.1139/cjm-44-5-456

J. E. Stewart, L. J. Marks, C. R. Wood, S. M. Risser, and S. Gray, Symbiotic relations between bacteria and the domoic acid producing diatom Pseudo-nitzschia multiseries and the capacity of these bacteria for gluconic acid/gluconolactone formation, Aquatic Microbial Ecology, vol.12, pp.211-221, 1997.
DOI : 10.3354/ame012211

J. Q. Su, X. R. Yang, Y. Y. Zhou, and T. L. Zheng, Marine bacteria antagonistic to the harmful algal bloom species Alexandrium tamarense (Dinophyceae), Biological Control, vol.56, issue.2, pp.132-138, 2011.
DOI : 10.1016/j.biocontrol.2010.10.004

W. G. Sunda, Trace metal interactions with marine phytoplankton, Biological Oceanography, vol.6, pp.411-442, 1988.

A. E. Thessen, H. A. Bowers, and D. K. Stoecker, Intra-and interspecies differences in growth and toxicity of Pseudo-nitzschia while using different nitrogen sources. Harmful Algae, pp.792-810, 2009.

A. E. Thessen, T. M. Soniat, Q. Dortch, and G. J. Doucette, Crassostrea virginica grazing on toxic and non-toxic diatoms, Toxicon, vol.55, issue.2-3, pp.570-579, 2010.
DOI : 10.1016/j.toxicon.2009.10.011

V. L. Trainer, M. L. Wells, W. P. Cochlan, C. G. Trick, B. D. Bill et al., An ecological study of a massive bloom of toxigenic Pseudo-nitzschia cuspidata off the Washington State coast, Limnology and Oceanography, vol.54, issue.5, pp.1461-1474, 2009.
DOI : 10.4319/lo.2009.54.5.1461

C. G. Trick, B. D. Bill, W. P. Cochlan, M. L. Wells, V. L. Trainer et al., Iron enrichment stimulates toxic diatom production in high-nitrate, low-chlorophyll areas, Proceedings of the National Academy of Sciences of the United States of America, pp.5887-5892, 2010.
DOI : 10.1073/pnas.0910579107

X. Wang, Z. J. Li, J. Q. Su, Y. Tian, X. R. Ning et al., Lysis of a red-tide causing alga, Alexandrium tamarense, caused by bacteria from its phycosphere, Biological Control, vol.52, issue.2, pp.123-130, 2010.
DOI : 10.1016/j.biocontrol.2009.10.004

M. L. Wells, C. G. Trick, W. P. Cochlan, M. P. Hughes, and V. L. Trainer, Domoic acid: The synergy of iron, copper, and the toxicity of diatoms, Limnology and Oceanography, vol.50, issue.6, pp.1908-1917, 2005.
DOI : 10.4319/lo.2005.50.6.1908

K. Yoshiyama, J. P. Mellard, E. Litchman, and C. A. Klausmeier, Phytoplankton Competition for Nutrients and Light in a Stratified Water Column, The American Naturalist, vol.174, issue.2, pp.190-203, 2009.
DOI : 10.1086/600113