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Dernières publications
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Dylan Moutachi, Janek Hyzewicz, Pauline Roy, Mégane Lemaitre, Damien Bachasson, et al.. Treadmill running and mechanical overloading improved the strength of the plantaris muscle in the dystrophin‐desmin double knockout (DKO) mouse. The Journal of Physiology, In press, ⟨10.1113/JP286425⟩. ⟨hal-04643936⟩
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Medhi Hassani, Dylan Moutachi, Mégane Lemaitre, Alexis Boulinguiez, Denis Furling, et al.. Beneficial effects of resistance training on both mild and severe mouse dystrophic muscle function as a preclinical option for Duchenne muscular dystrophy. PLoS ONE, 2024, 19, ⟨10.1371/journal.pone.0295700⟩. ⟨hal-04501283⟩
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Antonio Atalaia, Dagmar Wandrei, Nawel Lalout, Rachel Thompson, Adrian Tassoni, et al.. EURO-NMD registry: federated FAIR infrastructure, innovative technologies and concepts of a patient-centred registry for rare neuromuscular disorders. Orphanet Journal of Rare Diseases, 2024, 19 (1), pp.66. ⟨10.1186/s13023-024-03059-3⟩. ⟨hal-04460667⟩
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Florent Porquet, Lin Weidong, Kévin Jehasse, Hélène Gazon, Maria Kondili, et al.. Specific DMPK-promoter targeting by CRISPRi reverses myotonic dystrophy type 1-associated defects in patient muscle cells. Molecular Therapy - Nucleic Acids, 2023, 32, pp.857 - 871. ⟨10.1016/j.omtn.2023.05.007⟩. ⟨hal-04287597⟩
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Caroline Le Guiner, T Larcher, A Lafoux, G Toumaniantz, S Webb, et al.. Characterization of the muscular and cardiac diseases of the DMSXL mouse model, a transgenic mouse model for Myotonic Dystrophy type 1. American Society of Gene & Cell Therapy, May 2023, LOS ANGELES, United States. ⟨hal-04096181⟩
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Dylan Moutachi, Mégane Lemaitre, Clément Delacroix, Onnik Agbulut, Denis Furling, et al.. Valproic acid reduces muscle susceptibility to contraction‐induced functional loss but increases weakness in two murine models of Duchenne muscular dystrophy. Clinical and Experimental Pharmacology and Physiology, In press, ⟨10.1111/1440-1681.13804⟩. ⟨hal-04146953⟩
Chiffres clés
144
Publications avec texte intégral
Open Access
53 %
Mots clés
Centronuclear myopathy
Gene editing
PCR
Genotype phenotype correlation
Muscular dystrophy
Hypoxia
Aging
Acetylcholinesterase knockout mouse
Duchenne muscular dystrophy
Glucocorticoid-receptor
Muscle
GABA
Dilated cardiomyopathy
CTG repeat contractions
Diaphragm
Alternative splicing
Astrocytes
Antisense oligonucleotides
Myotonic dystrophy mouse models
Intermediate filament
ACETYLCHOLINESTERASE
Autophagy
Cells
Dystrophin
Animals
Trinucleotide Repeat Expansion
Thérapie génique
Myelin
CRISPR/Cas9
Brain
Long read sequencing
PacBio
Acute coronary syndrome
Glutamate
Myostatin
MBNL
Glial cells
Cultured
Heart
Dystrophie Myotonique
AAV
Maximal force
Skeletal muscle
Dystrophie myotonique
Therapy
Gene Therapy
DMSXL mice
Myotonic Dystrophy
Glucocorticoids
Humans
RNA splicing
Transcriptomics
Dynamin 2
Expression
Myotonic Dystrophy Type 1
CONGENITAL MYATHENIC SYNDROME
Desmin
DM1
Cardiac muscle
CTG repeats
Oligodendrocytes
Trinucleotide repeat expansion
Brain dysfunction
Transgenic mouse model
Cell culture model
Myotonic dystrophy
Cell penetrating peptide
Exercise
Male
Cell model
KNOCKOUT MICE
Neuron
Mouse models
Acetylcholinesterase deficiency
ARN
Myotonic Dystrophy type 1
Endurance training
Exercice
BIOLOGIE MOLECULAIRE
Motoneuron
Gene therapy
Astrocyte
CMS
CTG repeat instability
Myotonic dystrophy type 1
Mice
Oligodendrocyte
Heart failure
RNA interference
DMPK
Cytoskeleton
Fibrosis
Antisense oligonucleotide
Central nervous system
CRISPRi
Quantitative microdialysis
GSK3
Transgenic mouse
RNA biology
Mouse model