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Développement de nouveaux systèmes d’assurance qualité à base de sondes dosimétriques GaN pour la curiethérapie

Pierrick Guiral 1 
1 INL - CSH - INL - Conception de Systèmes Hétérogènes
INL - Institut des Nanotechnologies de Lyon
Abstract : This work aims to develop and characterize novel quality assurance systems based on Gallium Nitride (GaN) dosimeter probe for brachytherapy. It includes characterization and simulation studies of the GaN transducer and of the dosimeter probe as well as the implementation and testing of two quality assurance system prototypes.The radioluminescence properties of the GaN transducer have been studied for optimization of the dosimeter response. Characterization studies of dosimeter probes incorporating miniaturized GaN transducers have been carried out in the frame of the quality assurance systems development. Monte Carlo simulations of the GaN probe under irradiation has also been performed and compared with measurements.A method which processes simultaneously the output signals from several GaN probes has been proposed for real time determination of the projector’s physical parameters (dwell position, dwell time and activity of the source). Two quality assurance system prototypes implementing this method have been designed and fabricated: an instrumented phantom for pre-treatment quality assurance and an instrumented gynecological applicator for in vivo quality control. These two prototypes have been tested and evaluated in clinical conditions and their main characteristics are satisfactory. Both systems are in line with the application requirements and offers new perspectives for quality assurance in brachytherapy
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Submitted on : Monday, October 2, 2017 - 8:05:05 PM
Last modification on : Saturday, September 24, 2022 - 2:58:04 PM


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  • HAL Id : tel-01603806, version 1


Pierrick Guiral. Développement de nouveaux systèmes d’assurance qualité à base de sondes dosimétriques GaN pour la curiethérapie. Physique Médicale []. Université de Lyon, 2017. Français. ⟨NNT : 2017LYSE1127⟩. ⟨tel-01603806⟩



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